- This page contains affiliate links. We may earn a commission at no extra cost to you.
Alabama (4-1) at Missouri (5-0)
- When: Oct 11 2025, 12:00 PM
- Where: Memorial Stadium/Faurot Field, Columbia, MO
- Where to watch: ABC
- Last Meeting: Alabama 34-0, October 26th, 2024
(8) Alabama vs (14) Missouri Preview & Prediction
Spread: Alabama -3.0
Moneyline: Alabama (-165)
Total: 51.5
Alabama Crimson Tide Betting Outlook
The No. 8 Alabama Crimson Tide head to Columbia with confidence and momentum after four straight wins. Following a narrow season-opening loss to Florida State, Alabama has since taken down Georgia and Vanderbilt, reminding everyone that the Tide still belong among the nation’s elite.
Quarterback Ty Simpson has turned into a breakout star, leading the SEC in passing yards (1,478) and touchdowns (13) while throwing just one interception in five games. His accuracy and poise have revitalized the offense, and head coach Kalen DeBoer continues to stress discipline and focus. The Tide defense, meanwhile, is holding opponents to just over 17 points per game, thriving on third-down stops and red-zone discipline.
Still, Alabama’s challenge lies in keeping its edge away from home against an undefeated team with something to prove. If the Crimson Tide establish the run early and keep Simpson upright, they’ll be in prime position to extend their dominance over Missouri.
Prediction for Alabama: Expect Simpson and the Tide offense to find rhythm late and control the tempo behind a strong defensive effort.
Missouri Tigers Betting Outlook
The No. 14 Missouri Tigers enter this one with a spotless 5-0 record and plenty of swagger. They haven’t left home all season, and their 15-game home winning streak is the second-longest in the country. However, they’re about to face their toughest test yet.
Quarterback Beau Pribula, who took over after Sam Horn’s season-ending injury, has exceeded expectations with 1,203 yards and nine touchdowns while showing composure against weaker defenses. Running back Ahmad Hardy has been electric, leading the nation with 730 rushing yards and adding nine scores on the ground. Missouri’s attack has averaged a robust 45.2 points per game, though that number will be tested against an Alabama defense that rarely breaks.
Coach Eli Drinkwitz knows this game will define how real Missouri’s hot start truly is. To pull the upset, the Tigers need to protect Pribula, establish Hardy early, and turn home-field energy into sustained pressure.
Prediction for Missouri: Expect a spirited start and plenty of fireworks, but sustaining offensive rhythm against Alabama’s front seven may prove difficult.
Final Score Prediction
The Tide’s defense makes the difference late as Simpson outduels Pribula in a statement road win that snaps Missouri’s home streak.
Final Score: Alabama 31, Missouri 24
Lean: Alabama -3.0
Total: Over 51.5
- NCAA Football Odds source: Bovada Sportsbook
- Get real-time live scores & latest betting odds here!
