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Arizona (64-67) at Milwaukee (81-50)
- When: Aug 25 2025, 7:40 PM
- Where: American Family Field, Milwaukee
- Where to watch: FDSWI
Diamondbacks vs. Brewers – Game Betting Preview & Prediction
Moneyline: Milwaukee -182
Spread: Milwaukee -1.5 (+115)
Total: 8.0
Milwaukee Brewers Betting Outlook
The Brewers open this four-game home set as moneyline favorites -182 with the total sitting at 8.0 runs. Milwaukee will turn to Brandon Woodruff, who’s looking to rebound after his roughest outing of the season. The Cubs tagged him for three runs in just over four innings last week, but manager Pat Murphy was more encouraged by the fact that Woodruff stretched to 94 pitches, the highest total since his return from major shoulder surgery in late July.
Since rejoining the rotation, Woodruff has posted a 4-1 record with a 2.47 ERA, showing flashes of his All-Star form. Against Arizona, however, his track record has been mixed, 2-1 with a 4.28 ERA across seven appearances. The Brewers have also slowed down since their remarkable 14-game win streak earlier this month, dropping six of their last nine games. Late-inning issues have crept up too, with closer Trevor Megill blowing consecutive save opportunities against the Giants over the weekend.
Arizona Diamondbacks Betting Outlook
The Diamondbacks enter this matchup after winning two of three at home against Cincinnati, though their four-game winning streak ended with a 6-1 loss Sunday. Arizona’s lineup continues to show grit, but they’ll need more consistency if they want to make noise in Milwaukee.
Eduardo Rodriguez gets the start, carrying a 5-7 record with a 5.40 ERA. While his season overall has been shaky, he’s had relative success against the Brewers in his career, holding a 2.60 ERA in three starts. In 2025, though, he’s 0-1 with a 2.84 ERA versus Milwaukee. If Rodriguez can limit the long ball and give Arizona length, the D-backs have a shot to hang around.
MLB Final Betting Outlook
This matchup leans heavily toward Milwaukee with Woodruff on the mound, especially given Arizona’s struggles to generate offense against elite pitching. The Brewers’ bullpen has been shaky of late, but Woodruff’s extended pitch count suggests he can go deeper this time around. Rodriguez has been inconsistent, and that could spell trouble against a Milwaukee lineup eager to bounce back.
Score Prediction: Brewers 5, Diamondbacks 2
Pick: Milwaukee -1.5 (+115)
Total: Under 8.0 (-111)
- MLB Odds source: MyBookie Sportsbook
- Get real-time live scores & latest betting odds here!
