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Boise State vs South Florida Prediction & Odds Preview

Boise State favored vs South Florida. Expert odds, matchup breakdown and score prediction for Thursday night’s clash.

(Photo by Getty Images) Maddux Madsen
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Boise State (0-0) at South Florida (0-0)

  • When: Aug 28 2025, 5:30 PM
  • Where: Raymond James Stadium, Tampa, FL
  • Where to watch: ESPN
  • Last Meeting: No previous meeting

(25) Boise State vs South Florida Preview & Prediction

Spread: Boise State -5.5
Moneyline: Boise State -220
Total: 61.5

Boise State Broncos Betting Outlook

Boise State kicks off the post-Ashton Jeanty era as a 5.5-point favorite with the total set at 61.5. Jeanty’s record-setting 2,600+ yard season and Heisman runner-up campaign powered the Broncos to the College Football Playoff, but with him now in the NFL, the team must reinvent its ground game.

Enter Malik Sherrod, a veteran transfer from Fresno State, and Sire Gaines, a redshirt freshman. Together, they’ll attempt to anchor the run-heavy identity head coach Spencer Danielson insists won’t change. Boise also returns quarterback Maddux Madsen, who threw for over 3,000 yards and 23 touchdowns last season, giving the Broncos some stability under center.

The challenge? Adjusting to Florida humidity and keeping their momentum without Jeanty. But make no mistake, this is still a team built to contend.

South Florida Bulls Betting Outlook

USF opens 2025 facing a brutal gauntlet: Boise State, Florida, and Miami. Yet head coach Alex Golesh welcomes the challenge, framing it as a chance for the Bulls to prove they belong in marquee matchups.

The good news? Quarterback Byrum Brown is back. After a stellar 2023 season with over 4,100 combined yards and 37 total touchdowns, his 2024 campaign was derailed by injury. Healthy again, Brown has the tools to cause problems with both his arm and legs.

The Bulls have also won back-to-back bowl games under Golesh, creating some momentum heading into this test. Playing at Raymond James Stadium on national TV, they’ll aim to seize the moment and shock a ranked opponent.

Prediction and Gambling Angle

Boise State has the better roster depth and should lean on their defense to control the game, but South Florida’s dual-threat QB makes them dangerous at home. Expect USF to hang around early, but the Broncos’ balance wins out.

Final Score:  Boise State 34, South Florida 27
Lean: Boise State -5.5
Total: 
Under 61.5 

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