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Floyd Mayweather vs Manny Pacquiao Boxing Odds & Betting Props

Event: Mayweather vs. Pacquiao 2
Date:  Saturday, September 19, 2026
Venue: The Sphere
Location: Las Vegas, Nevada, United States

Circle September 19 on the betting calendar. Floyd Mayweather Jr. and Manny Pacquiao are set to run it back at the Sphere means in Las Vegas, with the global stream landing on Netflix. Yes, that rivalry is officially back in the market.

Mayweather recently hinted at another comeback after his 2026 exhibition with Mike Tyson and inked a multifight deal with CSI Sports and Fight Sports. Pacquiao returned last July, fighting WBC welterweight champ Mario Barrios to a majority draw, and will tune up in an April 18 exhibition against Ruslan Provodnikov at the Thomas and Mack Center.

Expect odds, props and nostalgia to collide in a massive rematch handle.

Here are the Live Odds & Props:

Updated: February 24, 2026

Floyd Mayweather vs Manny Pacquiao
To Win the Bout

Floyd Mayweather   -175
Manny Pacquiao   +135

Boxing Odds & Props source: BetUS Sportsbook

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