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Buffalo (9-4-0) at New England (11-2-0)
- When: Dec 14 2025, 1:00 PM
- Where: Gillette Stadium, Foxborough, MA
- Where to watch: CBS
- Last Meeting: NE 23-20, October 5th, 2025
Buffalo vs New England Preview & Prediction
Spread: Buffalo -1.5
Moneyline: Buffalo (-125)
Total: 49.0
New England Patriots Breakdown
New England finally finds itself back in a position it once treated as routine but now feels brand new. The Patriots can reclaim the AFC East and punch a playoff ticket with a win at home, something that has not happened in several seasons. After dominating the division for more than a decade, this moment represents a full circle opportunity for a franchise that has rebuilt its identity piece by piece.
The Patriots enter riding a massive winning streak and already proved they can beat Buffalo earlier this season. Despite that momentum, New England still opens as the home underdog, which has only added fuel to the locker room. This roster is filled with players who feel overlooked, and that edge has shown up on the field week after week.
Quarterback Drake Maye continues to grow into the role, using his arm strength and mobility to stress defenses. Protection will be key after Buffalo generated pressure in the earlier meeting, though the potential return of an interior lineman helps stabilize things up front. New England’s success hinges on playing clean football, controlling tempo, and forcing Buffalo to earn everything in a loud and emotional environment.
Buffalo Bills Breakdown
Buffalo arrives as a 1.5 point road favorite with the total set at 49.0, still firmly focused on playoff positioning. The Bills have owned this division for years, and they understand exactly what is on the line even if they are not publicly hyping it up. Josh Allen has delivered some of his best performances against top competition this season, and that trend gives Buffalo confidence heading into a hostile setting.
Allen’s dual threat ability remains the engine of the offense, and Buffalo thrives when he dictates the pace. The Bills defense has also found timely playmakers, particularly in the secondary, creating game changing moments that flip momentum quickly. That opportunistic style is dangerous against a young quarterback, even one playing with confidence.
The Bills know New England will be motivated, but Buffalo has been here before and understands how to manage pressure games late in the season.
Prediction and Betting Outlook
This matchup feels like a playoff game, and the number reflects how tight it should be. New England’s streak and home field keep this close, but Buffalo’s experience in high leverage moments and Allen’s ability to elevate against elite opponents give the Bills a narrow edge late.
Final Score: Bills 26, Patriots 20
Lean: Buffalo -1.5
Total: Under 49.0
- NFL Football Odds source: Bovada Sportsbook
- Get real-time live scores & latest betting odds here!
