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Buffalo (7-4-0) at Pittsburgh (6-5-0)
- When: Nov 30 2025, 4:25 PM
- Where: Acrisure Stadium, Pittsburgh, PA
- Where to watch: CBS
- Last Meeting: BUF 31-17, January 15th, 2024
Buffalo vs Pittsburgh Preview & Prediction
Spread: Buffalo -3.0
Moneyline: Buffalo (-170)
Total: 45.5
Buffalo Bills Betting Outlook
The Bills arrive at Acrisure Stadium looking like a team that misplaced its car keys, found them again, and still managed to lock themselves out. Buffalo has been unpredictable all year, but Josh Allen still walks into stadiums with the quiet confidence of a man who knows he can casually throw for 300 yards while eating a sandwich.
Of course, last week he was sacked eight times in Houston which is roughly the number of times your phone autocorrects a simple word into a disaster. Now Allen gets to face a Steelers defense that he has historically treated like a personal piñata. Four wins in five meetings and a playoff beatdown testify to that.
The biggest problem for Buffalo? Two missing offensive tackles. So Allen may be improvising like a jazz musician trapped inside a collapsing pocket. Still, the Bills offense tends to find a way, even when half the fanbase is yelling at their TV.
Buffalo needs this win badly to keep the AFC East dream alive and avoid being stuck behind New England like a slow driver in the left lane.
Pittsburgh Steelers Betting Outlook
Mike Tomlin loves urgency, and nothing screams urgency like dropping four of six and suddenly watching your playoff chances shrink faster than a dollar menu item. The Steelers started 4 and 1, but then remembered that consistency is optional and offense is apparently a luxury.
Good news though: Aaron Rodgers is back after the wrist injury. Bad news: he returns to face a Buffalo team desperate enough to blitz the equipment staff if necessary.
The Steelers defense has not been itself lately. Five different teams scored 31 or more on them. Even Chicago put up points which should be physically impossible. If Pittsburgh wants a shot, the defense must resurrect its old form and hope Watt terrorizes whoever Buffalo drags in at tackle.
The vibe around Pittsburgh is simple. It is cold. It is late November. It is stress season. And Tomlin knows it.
Prediction: Bills at Steelers
Both teams are flawed and both need this game like a gambler needs one more parlay that definitely will not hit. But Buffalo has the better quarterback, more firepower, and a slightly smaller degree of chaos.
Final Score: Bills 24, Steelers 20
Lean: Buffalo -3.0
Total: Under 45.5
- NFL Football Odds source: Bovada Sportsbook
- Get real-time live scores & latest betting odds here!
