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Columbia vs No. 4 UConn Betting Odds, Picks & Prediction

College basketball preview with Columbia vs UConn odds, spread, and expert betting prediction.

(Photo by Getty Images) Alex Karaban
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Columbia (1-0) vs UConn (2-0)

  • When: Nov 10 2025, 6:30 PM
  • Where: Harry A. Gampel Pavilion, Storrs, CT, USA
  • Where to watch: Fox Sports 1

Columbia vs (4) UConn Preview & Prediction

Spread: UConn -33.5
Moneyline: N/A
Total: 155.0

UConn Huskies Betting Preview

The fourth-ranked Huskies are back in Storrs looking to finish their three-game homestand with another statement win. UConn (2-0) has looked every bit like a national powerhouse to start the season, outscoring its opponents by a combined 93 points through two games. Their 110-47 dismantling of UMass Lowell showcased both dominance and depth, with the Huskies firing on all cylinders from the opening tip.

Big man Tarris Reed Jr. returned from a hamstring injury and wasted no time making his presence felt, posting 20 points, 12 rebounds, and four blocks. Head coach Dan Hurley praised the team’s defensive intensity after the blowout, saying their aggression and focus finally matched the standard he demands. With seven players scoring in double figures and Reed still on a minutes restriction, UConn’s talent pool runs deep.

Hurley’s group has won 35 straight nonconference home games and is a heavy 33.5-point favorite in this matchup. The Huskies’ combination of length, shooting, and tempo makes them nearly unstoppable when clicking, especially on their home floor. Their offensive firepower should once again overwhelm Columbia if they bring the same energy as Friday night.

Columbia Lions Betting Preview

Columbia enters this game with a bit of momentum after starting the Kevin Hovde era with a 71-53 victory over New Haven. The Lions played disciplined basketball on both ends, shooting over 55 percent from the field and dominating the glass with a +14 rebound margin. That kind of control and composure will be vital as they step up in competition against one of the nation’s best teams.

Kenny Noland led the way with 14 points, while freshman Miles Franklin and senior Avery Brown chipped in double figures. The Lions’ depth stood out, 11 players saw minutes, a theme Hovde says will continue as he looks to keep fresh legs in rotation. Columbia returns four seniors and most of last year’s production, giving them some veteran presence in what will easily be their toughest test yet.

The challenge for Columbia will be keeping pace with UConn’s relentless pace and size. Even with improved shooting and balance, they’ll need to take care of the ball and hit from deep to stay within striking distance.

Prediction & Betting Angle

UConn’s dominance at home and superior depth make this matchup feel lopsided from the jump. Columbia’s effort and balanced scoring are positives, but the Huskies’ defensive pressure and transition offense should break things open early. Expect Hurley’s squad to stay sharp and keep the momentum rolling heading into tougher competition ahead.

Final Score:  UConn 97, Columbia 60
Lean:  UConn -33.5
Total: 
Over 155.0 

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