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No. 3 LSU vs Florida Betting Odds, Preview & Prediction

Florida and LSU will both be gunning for a victory when they meet at Tiger Stadium.

(Photo by Getty Images) Garrett Nussmeier
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Florida (1-1) at LSU (2-0)

  • When: Sep 13 2025, 7:30 PM
  • Where: Tiger Stadium, Baton Rouge, LA
  • Where to watch: ABC
  • Last Meeting: Florida 27-16, November 16th, 2024

Florida vs (3) LSU Preview & Prediction

Spread: LSU -5.0
Moneyline: LSU (-284)
Total: 47.5

LSU Tigers Betting Outlook

The Tigers sit at 2-0 and come into this SEC opener with plenty of buzz after their statement road win over Clemson. Still, last week’s 23-7 victory over Louisiana Tech showed some cracks, especially in the run game. LSU averaged just 3.8 yards per carry, settling for field goals too often in the red zone.

Defensively, LSU has been rock-solid, allowing only 17 total points across two games. With a secondary built to frustrate big plays, LSU is well-positioned to dictate the pace. Playing at home in Death Valley on a Saturday night, the Tigers have both the momentum and the crowd behind them.

Player Prop Pick – LSU: Aaron Anderson Over 66.5 Receiving Yards. With red zone struggles, expect LSU to air it out more.

Florida Gators Betting Outlook

Florida enters with a 1-1 record, and the shine from its preseason ranking has already faded. After a dominant opener against Long Island, the Gators fell flat at home versus South Florida, losing 18-16. Questions about Billy Napier’s leadership are resurfacing, but this rivalry game gives Florida a chance to reset.

Quarterback DJ Lagway has shown flashes of his elite arm strength, though rust and limited preseason reps have slowed him. Against LSU’s defense, efficiency will be critical. Florida’s defense has held up well in spurts, but consistency will be tested in Baton Rouge.

Player Prop Pick – Florida: DJ Lagway Over 1.5 Passing Touchdowns. Florida will need him to take risks to keep pace.

Expert Betting Outlook & Prediction

LSU has the talent edge and home-field advantage, while Florida is still searching for its rhythm. Expect the Tigers’ defense to limit big plays and their offense to do just enough to cover the spread.

Final Score:  LSU 27, Florida 17
Lean: LSU -7.0
Total: 
Under 47.5 

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