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Detroit vs Green Bay Prediction: Thanksgiving Clash

Thanksgiving NFL: Packers vs Lions betting preview with odds and matchup insight.

(Photo by Getty Images) Jared Goff
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Green Bay (7-3-1) at Detroit (7-4-0)

  • When: Nov 27 2025, 1:00 PM
  • Where: Ford Field, Detroit, MI
  • Where to watch: FOX
  • Last Meeting: GB 27-13, September 7th, 2025

Green Bay vs Detroit Preview & Prediction

Spread: Detroit -3.0
Moneyline: Detroit (-165)
Total: 48.0

Green Bay Packers Betting Breakdown

The Packers roll into Thanksgiving knowing this matchup could shape the entire NFC North race by the time the season ends. Even though Chicago sits atop the division standings for now, Green Bay is still positioned as the betting favorite to take the crown, and a win here would give them the season sweep over Detroit. That would be a massive tiebreaker advantage heading into December.

Green Bay’s defense continues to lean heavily on Micah Parsons’ chaos-creating talent. Parsons grabbed his 10th sack last week and joined Reggie White as the only players since 1982 to open their careers with five straight double-digit sack seasons. He was a problem in Week 1 against Detroit, and the Packers will try to unleash him again.

Offensively, Green Bay hopes to take advantage of Detroit’s banged-up secondary, especially with injuries piling up for the Lions. The one big question for the Packers is whether running back Josh Jacobs will be healthy enough to factor in. His status could significantly influence how Green Bay approaches this matchup.

Green Bay Prediction Angle: If the Packers can lock down Detroit’s run game again and Parsons gets his usual disruption, Green Bay keeps this tight into the fourth quarter.

Detroit Lions Betting Breakdown

Detroit is chasing history too, aiming for its third straight division title. This is the kind of game that decides whether they stay in that hunt or get shoved into the wild-card crowd. The Lions know this and will have Ford Field roaring early.

The offense is powered by Jahmyr Gibbs, who has exploded lately after being contained in the first meeting. His 264-yard outburst and walk-off 69-yard score last week were reminders of the type of game-breaking threat he brings. Detroit needs that version of Gibbs again with several defensive starters unavailable, including Kerby Joseph and Terrion Arnold.

Aidan Hutchinson, after shaking off months of rust earlier in the season, has returned to form with 8.5 sacks and a monster performance against the Giants that included six quarterback hits. Detroit will need him to chase Jordan Love all night.

Detroit Prediction Angle: If Gibbs finds space and Hutchinson gets consistent pocket pressure, Detroit has the firepower to control this game at home.

Final Score Prediction

Detroit’s offense hits more explosive shots, and Ford Field energy tilts the final possession.

Final Score:  Lions 27, Packers 23
Lean:  Detroit -3.0
Total: 
Over 48.0 

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