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Houston vs Indy Odds, Total and Final Score

Texans vs Colts betting preview with odds, matchup analysis, and final score prediction for Week 18.

(Photo by Getty Images) C.J. Stroud
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Indianapolis (8-8-0) at Houston (11-5-0)

  • When: Jan 4 2026, 1:00 PM
  • Where: NRG Stadium, Houston, TX
  • Where to watch: CBS
  • Last Meeting: HOU 20-16, November 30th, 2025

Indianapolis vs Houston Preview & Prediction

Spread: Houston -11.0
Moneyline: Houston (-600)
Total: 39.5

Houston Texans Betting Breakdown

Houston’s turnaround has been nothing short of remarkable. After stumbling out of the gate, the Texans caught fire and now roll into the finale riding an eight game winning streak and another playoff berth already secured. Momentum is real in the NFL, and Houston has plenty of it.

The defense has been the backbone of this surge. Houston limits both passing and rushing production, forces turnovers, and consistently wins at the line of scrimmage. They pressure quarterbacks, disguise coverages well, and rarely give up explosive plays. With playoff positioning still technically in play, there is no incentive for Houston to coast.

Offensively, the Texans remain efficient and balanced. With confidence high and the defense setting short fields, Houston has been able to control games without taking unnecessary risks. This feels like a team treating Week 18 as a tune up rather than a formality.

Indianapolis Colts Betting Breakdown

Indianapolis started the season looking like a playoff lock and now limps into the finale after losing seven of its last eight games. Injuries, inconsistency, and instability at quarterback have all taken their toll.

The Colts turn to a rookie quarterback making his first NFL start, which adds uncertainty to an offense already struggling to sustain drives. Jonathan Taylor remains the focal point, but recent weeks have shown that even elite backs can be neutralized when defenses load the box and dare inexperienced quarterbacks to throw.

Defensively, Indianapolis has battled, but extended time on the field and poor offensive support have worn this unit down. Morale is strong internally, but execution has fallen off sharply against playoff caliber opponents.

Betting Outlook and Final Prediction

Houston is sharper, healthier, and playing with purpose. Indianapolis is evaluating the future and trying to survive the present. The Texans defense should dictate the flow early, and once Houston builds a lead, they are well equipped to protect it.

This sets up as a controlled, lower scoring game where Houston steadily pulls away rather than explodes offensively.

Final Score: Texans 24, Colts 10
Lean: Houston -11.0
Total: 
Under 39.5 

2026 CFP National Championship

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