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Kansas City (5-4-0) at Denver (8-2-0)
- When: Nov 16 2025, 4:25 PM
- Where: Empower Field at Mile High, Denver, CO
- Where to watch: Denver, CO
- Last Meeting: DEN 38-0, January 5th, 2025
Kansas City vs Denver Preview & Prediction
Spread: Kansas City -4.5
Moneyline: Kansas City (-225)
Total: 45.5
Denver Broncos Betting Preview
Denver enters this matchup catching 4.5 at home, sitting at 8 2 despite winning in the ugliest and most effective way imaginable. The Broncos lead the league in three-and-outs, penalties and criticism, yet they sit atop the AFC West because their pass rush has been completely overwhelming. A massive plus 35 sack differential has buried opponents and masked offensive inconsistency.
Bo Nix has embraced the winning-by-any-means identity, emphasizing that style points mean nothing when you’re stacking victories. Despite major injuries to Patrick Surtain II, J.K. Dobbins and leading tackler Alex Singleton, Denver continues to rely on next man up toughness and a defense that dictates games. With a perfect home record since last October, the Broncos believe this is their moment to prove they’re for real.
Kansas City Chiefs Betting Preview
Kansas City arrives at 5 4, laying 4.5 on the road after a much-needed bye week. The Chiefs are uncharacteristically scrambling for rhythm, and Patrick Mahomes hasn’t looked fully settled behind an offensive line dealing with injuries and rotation. But desperate teams are dangerous, and Kansas City still has firepower with Rashee Rice, Xavier Worthy, plus the expected returns of multiple starting tackles.
Andy Reid historically dominates after a bye, holding a 27 4 record when given extra preparation time. The Chiefs may be without Isiah Pacheco, which pushes more responsibility onto Kareem Hunt and rookie Brashard Smith. The biggest challenge will be surviving Denver’s pass rush without letting negative plays snowball, something Mahomes acknowledged as priority number one.
NFL Prediction & Betting Angle
Denver’s defense is elite, and their home-field advantage has been undeniable. But Kansas City is rested, healthier and entering its most urgent stretch of the season. Expect a tight, physical divisional game with late-game execution deciding it.
Final Score: Chiefs 24, Broncos 20
Lean: Denver +4.5
Total: Under 45.5
- NFL Football Odds source: Bovada Sportsbook
- Get real-time live scores & latest betting odds here!
