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49ers Aim to Stay Sharp vs. Rival Rams at Home

Divisional bragging rights will be on the line when the Rams and the 49ers meet at Levi’s Stadium.

(Photo by Getty Images) Brock Purdy

LA Rams (7-6-0) at San Francisco (6-7-0)

  • When: Dec 12 2024, 8:15 PM
  • Where: Levi’s Stadium, Santa Clara, CA
  • Where to watch: Amazon Prime Video

Game Odds, Spread, Moneyline & Total

Los Angeles Rams @ San Francisco 49ers
Moneyline

Los Angeles Rams   +125
San Francisco 49ers   -145

Los Angeles Rams @ San Francisco 49ers
Point Spread

Los Angeles Rams   2.5 (EVEN)
San Francisco 49ers   -2.5 (-120)

Los Angeles Rams @ San Francisco 49ers
Total

Over   49.0 (-110)
Under   49.0 (-110)

Key Players:
LA Rams: Matthew Stafford
San Francisco: Brock Purdy

Team Stats

Rams   49ers
7-6 Record 6-7
3-3 Away & Home 4-3
6-7-0 ATS 5-8-0
7-6-0 O/U 7-6-0

Last Matchup:
LAR 27-24, September 22nd, 2024

Game Preview

The San Francisco 49ers’ season has been a rollercoaster of injuries, and now they face another uphill battle as they host the Los Angeles Rams on Thursday night in Santa Clara. For bettors eyeing this matchup, there’s plenty of intrigue as the 49ers fight for their playoff lives, while the Rams aim to solidify their postseason hopes.

San Francisco’s Injury Woes

The 49ers (6-7) are in a precarious position, sitting at the bottom of the NFC West. To keep their playoff chances alive, they’ll need to win out against tough opponents like the Rams, Dolphins, Lions, and Cardinals. Unfortunately, injuries have been a recurring nightmare.

Christian McCaffrey, their offensive cornerstone, was sidelined for the season after just four games, and backup Jordan Mason joined him on injured reserve in Week 13. Rookie Isaac Guerendo stepped up with an impressive 78-yard, two-touchdown performance against the Bears last Sunday, but he’s now questionable with a foot sprain.

San Francisco’s injury list doesn’t stop there. Defensive end Nick Bosa, offensive linemen Trent Williams and Ben Bartch, and linebacker Dre Greenlaw are all dealing with various ailments. Bettors should monitor these statuses closely, as they significantly impact the 49ers’ performance on both sides of the ball.

Rams’ Momentum and Betting Outlook

In contrast, the Rams (7-6) are riding high after a thrilling 44-42 victory over the Buffalo Bills. Matthew Stafford is in peak form, throwing for 320 yards and two touchdowns last week, while Puka Nacua torched the Bills’ defense with 12 catches for 162 yards and a touchdown. Kyren Williams also contributed two rushing touchdowns, showcasing the Rams’ offensive versatility.

Los Angeles has won six of its last eight games, putting them in control of their playoff destiny. With matchups against all three NFC West rivals and the Jets remaining, this stretch will determine their postseason fate.

Adding to their arsenal, the Rams might welcome tight end Tyler Higbee back into the fold after his recovery from a torn ACL and MCL. Higbee practiced fully on Tuesday, and his return could bolster an already dynamic offense.

Key Trends and Predictions

– 49ers Against the Spread (ATS): Despite their struggles, San Francisco has shown resilience at home. However, their injury list and inconsistent performances make them a risky pick this week.

– Rams ATS: Los Angeles has been a strong play in recent weeks, covering in five of their last seven games. Their offense is firing on all cylinders, making them a tempting pick as a slight favorite.

– Over/Under: With both teams having injury concerns and inconsistent defenses, the over could be a valuable bet. The Rams’ high-scoring affair against the Bills last week highlights their ability to turn games into shootouts.

Betting Prediction

The Rams come into this game with momentum, healthier weapons, and a favorable matchup against a banged-up 49ers squad. While the Niners have home-field advantage, their offensive depth is stretched thin, and their defense could struggle against Stafford and company. Back the Rams on the moneyline, and consider the over on total points for added value.

Handicappers Picks – Join for Free

NFL Parlay Picks & Predictions

Final Score: LA Rams 31-24
Expert Pick: LA Rams (+125) & Over 49
A $100 Parlay Bet will return $430

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