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No. 15 Louisville vs. No. 16 Notre Dame College Football Odds & Picks

The Cardinals and the Fighting Irish will both be trying to pick up a win when they battle at Notre Dame Stadium.

(Photo by Getty Images) Riley Leonard
Game: Louisville Cardinals vs Notre Dame Fighting Irish

Date: Saturday, September 28, 2024

Location: Notre Dame Stadium in Notre Dame, IN

TV: Peacock

Odds/Point Spread: Fighting Irish (-6.5)

Total/Over-Under: 45

The Louisville Cardinals (3-0) face off against the Notre Dame Fighting Irish (3-1) at Notre Dame Stadium on Saturday, September 28, 2024. Notre Dame is favored by 6.5 points according to Bovada oddsmakers, with a total score of 45.

Carrying a 3-0 record this season, the Louisville Cardinals last defeated the Georgia Tech Yellow Jackets with a score of 31-19. They amassed 326 yards on 46 plays, with 57 rushing yards on 27 attempts. Their defense allowed 312 passing yards and 98 rushing yards in that game.

For the season, the Cardinals have accumulated 1,507 total yards, scoring 16 touchdowns without any turnovers. Defensively, they allow an average of 11.0 points per game.

The Notre Dame Fighting Irish, with a 3-1 record, defeated the Miami RedHawks 28-3 in their last game. They gained 270 rushing yards on 36 carries and allowed 110 rushing yards on 28 attempts in that matchup.

Notre Dame averages 412.0 yards per game with a rushing average of 238.3 yards. Their defense gives up 121.0 rushing yards and 135.3 passing yards per game.

In tonight’s game, the Cardinals are predicted to cover the spread with a +6.0 point advantage.

Free Pick: Take the Louisville Cardinals +6.5

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