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LSU (7-4) at Oklahoma (9-2)
- When: Nov 29 2025, 3:30 PM
- Where: Gaylord Family Oklahoma Memorial Stadium, Norman, OK
- Where to watch: ABC
- Last Meeting: LSU 37-17, November 30th, 2024
LSU vs (8) Oklahoma Preview & Prediction
Spread: Oklahoma -11.0
Moneyline: Oklahoma (-450)
Total: 36.0
Oklahoma Sooners Betting Outlook
Oklahoma arrives at 9 and 2 with everything to lose and everything to gain. After spending last season playing spoiler, the Sooners now sit in the opposite role, entering this matchup needing just one more win to secure a College Football Playoff spot. They have handled their November gauntlet well, taking down Tennessee, Alabama, and Missouri in consecutive weeks to strengthen their resume. Momentum is clearly swinging in their favor.
Linebacker Kip Lewis said it best. Oklahoma believes it has finally hit full stride, and the players want nothing to disrupt that rhythm. The defense has been the backbone of this late season surge, forcing eight turnovers in the past three games. The offense has been less dominant, especially after injuries altered their lineup, but limiting mistakes has been the key. With no turnovers in the last two games, the Sooners have embraced a cleaner, more controlled approach.
Oklahoma enters as an 11 point favorite, and with a total of 36, the expectation is a physical, slow burning defensive matchup. If the Sooners manage field position and avoid giving LSU short fields, they should stay in command. A win not only secures their playoff fate but also keeps their late season surge intact.
LSU Tigers Betting Outlook
LSU enters at 7 and 4, looking to finish a turbulent season with pride after a coaching change and midseason slide. Interim coach Frank Wilson has rallied his squad to back to back wins, restoring some confidence and giving the Tigers a chance to end on a high note. Wilson has emphasized legacy and self reflection, pushing players to compete like there is still plenty on the line.
Defensively, LSU remains among the nation’s toughest units. Their scoring defense, pass coverage, and run prevention all rank inside the top tier nationally. The challenge will be whether the offense can generate enough consistency with Michael Van Buren Jr. once again stepping in for injured quarterback Garrett Nussmeier. Van Buren has shown poise and anticipation, but the Tigers have limited margin for error against an Oklahoma defense playing its best football of the season.
The Tigers are also dealing with injury concerns at left tackle and in the backfield, but their identity rests on creating one on one mismatches and forcing offenses out of rhythm. If LSU’s defense can drag this into an ugly, low scoring contest, covering the 11 point spread becomes achievable.
Final Score Prediction & Betting Outlook
LSU’s defense will keep things competitive early, but Oklahoma’s defensive consistency and cleaner offensive execution give the Sooners the steadier path. With playoff stakes and home field energy behind them, Oklahoma does just enough to pull away in the second half but LSU cover.
Final Score: Oklahoma 23, LSU 15
Lean: LSU +11.0
Total: Over 36.0
- NCAA Football Odds source: Bovada Sportsbook
- Get real-time live scores & latest betting odds here!
