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Miami (0-2-0) at Buffalo (2-0-0)
- When: Sep 18 2025, 8:15 PM
- Where: Highmark Stadium, Orchard Park, NY
- Where to watch: Amazon Prime Video
Game Odds, Spread, Moneyline & Total
Miami Dolphins @ Buffalo Bills
Moneyline
Miami Dolphins +575
Buffalo Bills -900
Miami Dolphins @ Buffalo Bills
Point Spread
Miami Dolphins 11.5 (-110)
Buffalo Bills -11.5 (-110)
Miami Dolphins @ Buffalo Bills
Total
Over 50.5 (-115)
Under 50.5 (-105)
- Odds source: Bovada Sportsbook
- Get real-time live scores & latest betting odds here!
James Cook NFL Preview & Props
James Cook has been a steady presence in Buffalo’s backfield this season, showcasing his vision and ability to turn small openings into solid gains. Heading into Week 3, Cook remains a key part of the Bills’ offensive identity against the Dolphins.
Miami Dolphins @ Buffalo Bills
Anytime Touchdown Scorer
James Cook (BUF) -190
Miami Dolphins @ Buffalo Bills
Who will Score 2 or more Touchdowns?
James Cook (BUF) +230
Miami Dolphins @ Buffalo Bills
To Score 3 or more Touchdowns
James Cook (BUF) +1200
Miami Dolphins @ Buffalo Bills
Total Rush Attempts – James Cook
Over 15.5 (+120)
Under 15.5 (-160)
Miami Dolphins @ Buffalo Bills
Longest Rushing Attempt – James Cook (BUF)
Over 14.5 (-130)
Under 14.5 (EVEN)
Miami Dolphins @ Buffalo Bills
Total Rushing Yards – James Cook (BUF)
Over 67.5 (-135)
Under 67.5 (+105)
Miami Dolphins @ Buffalo Bills
Alternate Rushing Yards – James Cook (BUF)
To Record 30+ Rushing Yards -1700
To Record 40+ Rushing Yards -660
To Record 50+ Rushing Yards -350
To Record 60+ Rushing Yards -205
To Record 70+ Rushing Yards -130
To Record 80+ Rushing Yards +110
To Record 90+ Rushing Yards +175
To Record 100+ Rushing Yards +270
To Record 110+ Rushing Yards +360
To Record 125+ Rushing Yards +580
To Record 150+ Rushing Yards +1200
Miami Dolphins @ Buffalo Bills
Who will record the most Rushing Yards in the game?
James Cook (BUF) -160
Miami Dolphins @ Buffalo Bills
Total Receptions – James Cook (BUF)
Over 1.5 (-190)
Under 1.5 (+145)
Miami Dolphins @ Buffalo Bills
Alternate Receptions – James Cook (BUF)
To Record 1+ Receptions -1000
To Record 2+ Receptions -205
To Record 3+ Receptions +140
To Record 4+ Receptions +320
To Record 5+ Receptions +675
Miami Dolphins @ Buffalo Bills
Longest Reception – James Cook (BUF)
Over 8.5 (-120)
Under 8.5 (-110)
Miami Dolphins @ Buffalo Bills
Total Receiving Yards – James Cook (BUF)
Over 11.5 (-135)
Under 11.5 (+105)
Miami Dolphins @ Buffalo Bills
Alternate Receiving Yards – James Cook (BUF)
To Record 10+ Receiving Yards -180
To Record 15+ Receiving Yards -120
To Record 20+ Receiving Yards +120
To Record 25+ Receiving Yards +180
To Record 30+ Receiving Yards +275
To Record 40+ Receiving Yards +450
To Record 50+ Receiving Yards +700
To Record 60+ Receiving Yards +1050
To Record 70+ Receiving Yards +1700
To Record 80+ Receiving Yards +2500
Miami Dolphins @ Buffalo Bills
Total Rushing & Receiving Yards – James Cook (BUF)
Over 89.5 (-115)
Under 89.5 (-115)
James Cook Statistics
| Game | Rushing Att | Catches | Total Yards | Total TDs |
| 2 | 34 | 6 | 237 | 3 |
James Cook Past Results
| W | vs | Score | Yds | Att | Y/A | Lg | TD |
| 2 | @ |
W |
132 | 21 | 6.3 | 44 | 2 |
| 1 | W |
44 | 13 | 3.4 | 11 | 1 |
NFL Player Props Picks & Predictions
James Cook has steadily emerged as Buffalo’s lead back, averaging 85+ rushing yards in his first two games. Facing a Miami defense that’s struggled against the run, his workload and efficiency point toward another strong ground performance.
James Cook Props Pick: Total Rushing Yards –
Over 67.5 (-135)
A $135 Bet on that Props will return $235
- NFL Props source: Bovada Sportsbook