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Yankees vs Reds MLB Baseball Odds & Parlay Picks

NY Yankees and Cincinnati will meet on the field at Great American Ball Park in a battle of interleague teams.

(Photo by Getty Images) Max Fried

NY Yankees (45-34) at Cincinnati (42-38)

  • When: Jun 25 2025, 7:10 PM
  • Where: Great American Ball Park, Cincinnati
  • Where to watch: Amazon Prime

Yankees vs. Reds – Game Betting Preview & Prediction

Moneyline: NY Yankees -217 | Total: 9.5

Cincinnati Reds Preview

The Reds aren’t just winning, they’re doing it with late-game flair. Tuesday night’s electric 5-4 walk-off win marked their first comeback victory this year when trailing after six innings (they were 0-30). Credit top prospect Chase Burns, who debuted with flames, striking out eight Yankees, including his first five faced.

Trailing 3-0 in the 7th, Christian Encarnacion-Strand smacked a clutch three-run double, setting the stage for extra-inning dramatics. A crowd of nearly 40,000 witnessed the Reds scratch back in the 11th for a thrilling victory. That’s now three straight wins and five of the last six series taken by a team rediscovering its groove since a humbling June 4 loss to Milwaukee.

Brady Singer gets the nod for Cincinnati. He’s 7-5 with a 4.13 ERA and was solid in his last outing, allowing one run across six sweaty innings in St. Louis. But his track record vs. the Bronx Bombers? Not great, 0-2 in six previous starts with a 5.23 ERA.

Prediction from the Reds’ side: They’re playing with confidence and vibes are high, but they’ll need more than momentum to solve Fried.

New York Yankees Preview

What started as a dominant June has devolved into a mild identity crisis for the Yankees. Tuesday’s meltdown dropped them to 1-6 in extra innings this season and they haven’t won one on the road. They’ve now dropped 9 of their last 12 and scored just 34 runs during the slide.

Max Fried (9-2, 2.05 ERA) will try to stop the bleeding. He’s been the Yankees’ most consistent arm, tallying 12 quality starts, including six innings of three-run ball against the Orioles in his last outing. But he’s just 2-2 with a 4.58 ERA against the Reds in his career.

Aaron Judge continues to push a calm narrative, saying, “We’ve got winners here. We’ll bounce back.” But their AL East lead has dwindled from 5.5 games on June 1 to just one.

Prediction from the Yankees’ side: Backed into a corner and with Fried on the bump, New York is due to punch back.

Prediction & Betting Picks

With the Bronx bats eager to erupt and Fried steadying the ship, this feels like a classic bounce-back spot for the Yankees. Don’t expect another extra-innings heartbreaker, New York should cover the runline chalk and hold off the surging Reds to avoid the sweep.

Score Prediction: Yankees 6, Reds 3
Pick: NY Yankees RL -1.5 (-136)
Total: Under 9.5 (-125) 

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