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Oregon (4-0) at Penn State (3-0)
- When: Sep 27 2025, 7:30 PM
- Where: West Shore Home Field at Beaver Stadium, University Park, PA
- Where to watch: NBC
- Last Meeting: Oregon 45-37, December 7th, 2024
(6) Oregon vs (3) Penn State Preview & Prediction
Spread: Penn State -3.5
Moneyline: Penn State (-183)
Total: 52.5
Penn State Nittany Lions Betting Outlook
The Nittany Lions enter this matchup looking for revenge after Oregon spoiled their Big Ten title hopes last season. Penn State has circled this one on the calendar, and it’s no surprise it’s been declared a “White Out” game at Beaver Stadium. Over 110,000 screaming fans in white will make sure the Ducks feel the noise.
On the field, Penn State has been dominant defensively, ranking third nationally in scoring defense (just 5.7 points per game). Star linebacker Dani Dennis-Sutton has been everywhere, already tallying 4.5 tackles for loss and forcing two fumbles. On offense, Drew Allar leads the charge, supported by one of the best one-two running back punches in the country with Nicholas Singleton and Kaytron Allen. Last year, they gashed Oregon for nearly 300 rushing yards, and expect them to lean heavily on that formula again.
Player Prop Pick – Drew Allar: Over 1.5 passing touchdowns. His steady play-action work and red-zone efficiency make this appealing against Oregon’s secondary.
Oregon Ducks Betting Outlook
Oregon comes in red-hot, blasting through its schedule at 4-0 with an offense ranked seventh in scoring (50.8 ppg). New quarterback Dante Moore has been sensational, 962 passing yards and 11 touchdowns with only one interception. He shredded Oregon State last week with a career-high 305 yards and four scores. Moore’s poise and calm demeanor have stabilized the Ducks offense in a big way.
Tight end Kenyon Sadiq has quickly become a favorite target, with three scores already this season. Meanwhile, running back Noah Whittington is expected back after missing two games, which should give Oregon’s ground attack balance.
Player Prop Pick – Dante Moore: Over 222.5 passing yards. He’s been consistent and aggressive and Penn State’s defense will be tested deep.
Expert Prediction & Betting Angle
This one has all the makings of a playoff-type atmosphere. Penn State will try to control tempo with its ground game and suffocating defense, but Oregon’s offense isn’t going to fade quietly. Expect fireworks in a loud, back-and-forth thriller.
Final Score: Penn State 30, Oregon 27
Lean: Oregon +3.5
Total: Over 52.5
- NCAA Football Odds source: MyBookie Sportsbook
- Get real-time live scores & latest betting odds here!
