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Chicago Bulls vs 76ers Odds, Picks & Preview

Bulls look to stay unbeaten at home as the 76ers visit in a high-scoring clash.

(Photo by Getty Images) Josh Giddey
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Philadelphia (5-1) at Chicago (5-1)

  • When: Nov 4 2025, 8:00 PM
  • Where: United Center, Chicago, IL, USA
  • TV: CHSN

Philadelphia vs Chicago Preview & Prediction

Spread: Chicago -1.0
Moneyline: Chicago (-115)
Total: 239.5

Chicago Bulls Betting Outlook

The Bulls return home looking to bounce back after their first loss of the season, a 128-116 defeat to the Knicks. Chicago had been one of the NBA’s early surprises, holding opponents to just 30% shooting from three during their first five wins. That defensive edge vanished in New York, where the Knicks lit them up for nearly 48% from deep.

Josh Giddey led the charge with his first triple-double of the season (23 points, 12 assists, 11 rebounds), but it wasn’t enough to overcome a cold night defensively. The Bulls’ transition game thrives off misses, and when teams start hitting perimeter shots, they struggle to keep pace.

Nikola Vucevic remains the steady force inside, notching 17 points and 14 rebounds last game, continuing his trend of double-doubles. Chicago has been dominant at home this season (4-0), and they’ll need that United Center spark again as they look to reestablish their defensive identity.

Philadelphia 76ers Betting Outlook

The Sixers know how to recover from a setback, just look at their response to their first loss. Philadelphia bounced back by crushing Brooklyn 129-105, led by Kelly Oubre Jr.’s 29-point explosion and Tyrese Maxey’s relentless pace. Even without Joel Embiid (rest) and Paul George (knee recovery), Philly looked sharp, balanced, and motivated.

Head coach Nick Nurse continues to emphasize early energy and composure, traits that helped the Sixers build and maintain double-digit leads on the road. Philadelphia is perfect away from home (3-0), relying on Maxey’s speed and Oubre’s offensive confidence to push tempo and space the floor. If Embiid returns, it’s a major boost against a Bulls frontcourt that’s struggled to contain him historically.

NBA Prediction & Betting Angle

This matchup has a playoff-like feel early in the season. The Bulls’ defense will be tested by a Sixers team that spreads the floor and shoots efficiently, while Chicago’s inside presence could be key if Embiid sits again.

Expect a close, high-scoring affair with the Sixers’ depth and rhythm giving them the edge late.

Final Score:  Sixers 123, Bulls 119
Lean:  Philadelphia (-105)
Total: 
Over 239.5 

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