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San Francisco (3-1-0) at LA Rams (3-1-0)
- When: Oct 2 2025, 8:15 PM
- Where: SoFi Stadium, Inglewood, CA
- Where to watch: Amazon Prime Video
Game Odds, Spread, Moneyline & Total
San Francisco 49ers @ Los Angeles Rams
Moneyline
San Francisco 49ers +340
Los Angeles Rams -460
San Francisco 49ers @ Los Angeles Rams
Point Spread
San Francisco 49ers 8.5 (-105)
Los Angeles Rams -8.5 (-115)
San Francisco 49ers @ Los Angeles Rams
Total
Over 44.5 (-110)
Under 44.5 (-110)
- Odds source: Bovada Sportsbook
- Get real-time live scores & latest betting odds here!
Christian McCaffrey NFL Preview & Props
Christian McCaffrey continues to be a dual-threat nightmare, especially with the 49ers’ receiving corps banged up. Expect San Francisco to lean on his versatility in the short passing game. His quick burst, sharp cuts, and reliable hands make him a prime weapon against a Rams defense that’s had issues containing backs in space throughout the season.
San Francisco 49ers @ Los Angeles Rams
Anytime Touchdown Scorer
Christian McCaffrey (SF) -114
San Francisco 49ers @ Los Angeles Rams
First Touchdown Scorer
Christian McCaffrey (SF) +525
San Francisco 49ers @ Los Angeles Rams
Who will Score 2 or more Touchdowns?
Christian McCaffrey (SF) +350
San Francisco 49ers @ Los Angeles Rams
To Score 3 or more Touchdowns
Christian McCaffrey (SF) +2800
San Francisco 49ers @ Los Angeles Rams
Total Rush Attempts – Christian McCaffrey (SF)
Over 15.5 (-130)
Under 15.5 (EVEN)
San Francisco 49ers @ Los Angeles Rams
Total Rushing Yards – Christian McCaffrey (SF)
Over 59.5 (-115)
Under 59.5 (-115)
San Francisco 49ers @ Los Angeles Rams
Total Rushing Yards – Christian McCaffrey (SF)
Over – 1Q 14.5 (-115)
Under – 1Q 14.5 (-115)
San Francisco 49ers @ Los Angeles Rams
Alternate Rushing Yards – Christian McCaffrey (SF)
To Record 30+ Rushing Yards -1600
To Record 40+ Rushing Yards -600
To Record 50+ Rushing Yards -275
To Record 60+ Rushing Yards -150
To Record 70+ Rushing Yards +105
To Record 80+ Rushing Yards +170
To Record 90+ Rushing Yards +250
To Record 100+ Rushing Yards +375
To Record 110+ Rushing Yards +550
To Record 125+ Rushing Yards +875
San Francisco 49ers @ Los Angeles Rams
Who will record the most Rushing Yards in the game?
Christian McCaffrey (SF) +120
San Francisco 49ers @ Los Angeles Rams
Alternate Receptions – Christian McCaffrey (SF)
To Record 4+ Receptions -1600
To Record 5+ Receptions -600
To Record 6+ Receptions -275
To Record 7+ Receptions -160
To Record 8+ Receptions +110
To Record 9+ Receptions +180
To Record 10+ Receptions +275
To Record 11+ Receptions +450
San Francisco 49ers @ Los Angeles Rams
Who will record the most Receiving Yards in the Game?
Christian McCaffrey (SF) +525
San Francisco 49ers @ Los Angeles Rams
Total Receiving Yards – Christian McCaffrey (SF)
Over – 1Q 10.5 (-110)
Under – 1Q 10.5 (-120)
San Francisco 49ers @ Los Angeles Rams
Alternate Receiving Yards – Christian McCaffrey (SF)
To Record 20+ Receiving Yards -1600
To Record 25+ Receiving Yards -900
To Record 30+ Receiving Yards -550
To Record 40+ Receiving Yards -275
To Record 50+ Receiving Yards -150
To Record 60+ Receiving Yards +110
To Record 70+ Receiving Yards +180
To Record 80+ Receiving Yards +275
To Record 90+ Receiving Yards +400
To Record 100+ Receiving Yards +625
Christian McCaffrey Statistics
| Game | Rushing Att | Catches | Total Yards | Total TDs |
| 4 | 69 | 31 | 530 | 2 |
Christian McCaffrey Past Results
| Rushing | ||||||||
| W | vs | Score | Yds | Att | Y/A | Lg | TD | FUM |
| 4 | L
|
49 | 17 | 2.9 | 11 | 0 | 0 | |
| 3 | W
|
52 | 17 | 3.1 | 15 | 0 | 0 | |
| 2 | @
|
W
|
55 | 13 | 4.2 | 10 | 0 | 0 |
| 1 | @
|
W
|
69 | 22 | 3.1 | 13 | 0 | 0 |
| Receiving | ||||||
| W | Avg | Rec | Yds | LNG | TD | FUM |
|---|---|---|---|---|---|---|
| 4 | 15.3 | 6 | 92 | 29 | 1 | 1 |
| 3 | 8.8 | 10 | 88 | 20 | 0 | 0 |
| 2 | 8.7 | 6 | 52 | 14 | 1 | 0 |
| 1 | 8.1 | 9 | 73 | 25 | 0 | 0 |
NFL Player Props Picks & Predictions
Christian McCaffrey remains a go-to weapon in the 49ers’ passing game, especially with key receivers sidelined. Against a Rams defense that struggles with backs in coverage, his elite route running and reliable hands make 60+ receiving yards a realistic target.
Christian McCaffrey Props Pick: Alternate Receiving Yards –
To Record 60+ (+110)
A $100 Bet on that Props will return $210
- NFL Props source: Bovada Sportsbook
