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San Francisco (3-1-0) at LA Rams (3-1-0)
- When: Oct 2 2025, 8:15 PM
- Where: SoFi Stadium, nglewood, CA
- Where to watch: Amazon Prime Video
Game Odds, Spread, Moneyline & Total
San Francisco 49ers @ Los Angeles Rams
Moneyline
San Francisco 49ers +340
Los Angeles Rams -460
San Francisco 49ers @ Los Angeles Rams
Point Spread
San Francisco 49ers 8.5 (-105)
Los Angeles Rams -8.5 (-115)
San Francisco 49ers @ Los Angeles Rams
Total
Over 44.5 (-110)
Under 44.5 (-110)
- Odds source: Bovada Sportsbook
- Get real-time live scores & latest betting odds here!
Matthew Stafford NFL Preview & Props
Matthew Stafford enters Week 5’s Thursday Night Football clash looking sharp, with back-to-back strong outings under his belt. The veteran QB continues to showcase poise, arm strength, and command of the Rams’ offense. With key targets stepping up, Stafford’s timing and decision-making will be crucial as Los Angeles faces a shorthanded 49ers defense under the primetime lights.
San Francisco 49ers @ Los Angeles Rams
Anytime Touchdown Scorer
Matthew Stafford (LAR) +2000
San Francisco 49ers @ Los Angeles Rams
Who will Score 2 or more Touchdowns?
Matthew Stafford (LAR) +10000
San Francisco 49ers @ Los Angeles Rams
Result of First Passing Attempt – Matthew Stafford (LAR)
Complete -300
Incomplete +210
Interception +2500
San Francisco 49ers @ Los Angeles Rams
Total Passing Touchdowns – Matthew Stafford (LAR)
Over 1.5 (-150)
Under 1.5 (+115)
San Francisco 49ers @ Los Angeles Rams
Alternate Passing Touchdowns – Matthew Stafford (LAR)
To Record 1+ Passing Touchdowns -1000
To Record 2+ Passing Touchdowns -165
To Record 3+ Passing Touchdowns +225
To Record 4+ Passing Touchdowns +700
San Francisco 49ers @ Los Angeles Rams
Total Passing Attempts – Matthew Stafford (LAR)
Over 31.5 (-135)
Under 31.5 (+105)
San Francisco 49ers @ Los Angeles Rams
Total Completions – Matthew Stafford (LAR)
Over 21.5 (-120)
Under 21.5 (-110)
San Francisco 49ers @ Los Angeles Rams
Longest Pass Completion – Matthew Stafford (LAR)
Over 35.5 (-115)
Under 35.5 (-115)
San Francisco 49ers @ Los Angeles Rams
Total Passing Yards – Matthew Stafford (LAR)
Over 232.5 (-145)
Under 232.5 (+110)
San Francisco 49ers @ Los Angeles Rams
Alternate Passing Yards – Matthew Stafford (LAR)
To Record 150+ Passing Yards -1200
To Record 175+ Passing Yards -500
To Record 200+ Passing Yards -250
To Record 225+ Passing Yards -140
To Record 250+ Passing Yards +125
To Record 275+ Passing Yards +225
To Record 300+ Passing Yards +400
To Record 325+ Passing Yards +700
To Record 350+ Passing Yards +1100
San Francisco 49ers @ Los Angeles Rams
Who will have more Passing Yards in the game?
Matthew Stafford (LAR) +110
Mac Jones (SF) -145
Matthew Stafford Statistics
| Game | P. TDs | P. Yards | INT | Comp% | Rating |
| 4 | 8 | 1114 | 2 | 67.6 | 106.1 |
Matthew Stafford Past Results
| Passing | ||||||||
| W | vs | Score | Yds | CMP | ATT | Y/A | LNG | TD/Int |
| 4 | W
|
375 | 29 | 41 | 9.1 | 88 | 3/0 | |
| 3 | @
|
L
|
196 | 19 | 33 | 5.9 | 44 | 2/1 |
| 2 | @
|
W
|
298 | 23 | 33 | 9.0 | 40 | 2/1 |
| 1 | W
|
245 | 21 | 29 | 8.4 | 36 | 1/0 | |
| Russhing | ||||||
| W | Att | YDS | AVG | LNG | TD | FL |
|---|---|---|---|---|---|---|
| 4 | 4 | 4 | 1.0 | 6 | 0 | 0 |
| 3 | 0 | 0 | 0 | 0 | 0 | 0 |
| 2 | 2 | -6 | -3.0 | -2 | 0 | 0 |
| 1 | 4 | -2 | -0.5 | 0 | 0 | 0 |
NFL Player Props Picks & Predictions
Matthew Stafford has tossed 2+ passing TDs in three straight games and faces a 49ers defense missing key pieces. With strong chemistry building in the red zone and a high total on the board, Stafford is primed for multiple scores.
Matthew Stafford Props Pick: Total Passing Touchdowns –
Over 1.5 (-150)
A $150 Bet on that Props will return $250
- NFL Props source: Bovada Sportsbook
