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Tampa Bay (5-1-0) at Detroit (4-2-0)
- When: Oct 20 2025, 7:00 PM
- Where: Ford Field, Detroit, MI
- Where to watch: ABC/ESPN
- Last Meeting: TB 20-16, September 15th, 2024
Tampa Bay vs Detroit Preview & Prediction
Spread: Detroit -6.0
Moneyline: Detroit (-275)
Total: 52.5
Detroit Lions Betting Outlook
The Lions have turned resilience into a trademark. Detroit hasn’t lost back-to-back regular season games since October 2022, marking an incredible 50-game streak without consecutive defeats, the longest active run in the NFL. That consistency comes from head coach Dan Campbell’s “next man up” mentality, but the Lions face a real test against Tampa Bay after a tough loss to Kansas City.
Detroit’s defense looked shaky last week, and things won’t get easier with safety Brian Branch suspended and multiple defensive backs banged up. The secondary depth is thin, forcing the Lions to rely on pressure up front and quick adjustments in coverage. The expected return of defensive tackle Alim McNeill, who’s been out since tearing his ACL last season, should boost their interior defense.
Offensively, Jared Goff continues to be steady under center, but he’ll need more protection and cleaner execution if Detroit wants to avoid its first losing streak in nearly three years. The Lions have been dominant at home and should be motivated to bounce back against another NFC contender.
Tampa Bay Buccaneers Betting Outlook
Tampa Bay enters this primetime matchup sitting atop the NFC standings and showing a knack for winning close games. The Bucs have already claimed four victories by three points or fewer this season, proving they can thrive under pressure. Last week’s 30-19 win over San Francisco was their most complete performance yet, highlighted by an aggressive defensive front that racked up six sacks.
The defensive unit has been relentless, generating pressure on 15% of opponent dropbacks without heavy blitzing. Vita Vea and Lavonte David continue to anchor a disciplined front seven, while Yaya Diaby’s breakout as the team’s sack leader adds some youthful energy to Todd Bowles’ defensive schemes.
On offense, Baker Mayfield has found new life in Tampa Bay. The former No. 1 overall pick has been efficient, limiting turnovers and extending drives with smart decisions. Running back Rachaad White has been productive filling the lead role, piling up 157 scrimmage yards and three touchdowns over the past two games. The potential return of Mike Evans could give Mayfield the deep threat he’s been missing.
Final Score Prediction & Betting Outlook
This matchup pits Detroit’s grit against Tampa Bay’s opportunistic defense. The Lions have been nearly automatic in rebound games, and with Goff leading an offense that rarely stalls twice in a row, Detroit should reassert itself at home. Tampa Bay’s pass rush may keep things tight early, but Detroit’s offensive rhythm and home-field edge should take over in the second half.
Final Score: Lions 30, Buccaneers 21
Lean: Detroit -6.0
Total: Under 52.5
- NFL Football Odds source: Bovada Sportsbook
- Get real-time live scores & latest betting odds here!