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Rams vs Bucs Odds, Breakdown and Expert Prediction

Rams vs Buccaneers odds and expert betting prediction with spread, total and score pick.

(Photo by Getty Images) Puka Nacua
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Tampa Bay (6-4-0) at LA Rams (8-2-0)

  • When: Nov 23 2025, 8:20 PM
  • Where: SoFi Stadium, Inglewood, CA
  • Where to watch: NBC/Peacock
  • Last Meeting: TB 16-13, November 6th, 2022

Tampa Bay vs LA Rams Preview & Prediction

Spread: LA Rams -7.0
Moneyline: LA Rams (-396)
Total: 49.5

Tampa Bay Buccaneers Betting Outlook

Baker Mayfield strolling back into SoFi is basically a reunion tour mixed with a grudge match and just a dash of “remember what I did for you.” His five-game stint with the Rams resurrected his career, revived his confidence, and set him on the path to Tampa Bay’s current success.

Now he returns as a division-leading quarterback with playoff expectations, eager to show Sean McVay what a polished version of Baker looks like. The Bucs come in 6-4, winners of the NFC South, and Mayfield is playing some of the smartest ball of his career. Tampa’s offense is more efficient than flashy, but Baker’s legs have quietly become a real weapon again. He ran for 39 yards last week after a month of staying in the pocket.

The problem: Tampa’s defense has become a big play piñata. Four touchdowns allowed of 40 yards or more in their last two games, plus repeated breakdowns on special teams. If they give Stafford clean looks downfield, the Bucs are going to be in trouble fast.

Bucs Player Prop Pick: Baker Mayfield Over 13.5 Rushing Yards – He’s healthy again and running decisively.

Los Angeles Rams Betting Outlook

The Rams are 8-2 and rolling, but this week’s injury hits are no joke. Quentin Lake and Rob Havenstein landing on IR opens real cracks on both sides of the ball. LA will be relying on depth and patchwork adjustments, especially in coverage packages where Lake’s versatility was crucial.

Even with those issues, Matthew Stafford looks sharp and fully in sync with his weapons. His connection with Puka Nacua remains one of the most lethal combos in the league, and Tampa’s recent defensive lapses play right into what the Rams want to exploit. With backups stepping in at tight end and right tackle, LA will rely more on quick-game concepts and midrange strikes.

Defensively, the Rams have been consistent and disruptive all year and match up well against a Bucs offense that struggles to sustain long drives.

Rams Player Prop Pick: Puka Nacua Over 88.5 Receiving Yards – Tampa has been repeatedly torched deep and struggles with receivers who win early and late in routes.

Expert Betting Outlook & NFL Prediction

This matchup feels like a battle between Mayfield’s revenge storyline and a Rams team that is simply operating at a higher level. Tampa has too many explosive plays allowed, too many breakdowns on special teams, and too many liability spots for Stafford not to exploit.

The Bucs will move the ball, but the Rams’ consistency, efficiency, and home field should carry the day.

Final Score:  Rams 31, Buccaneers 23
Lean:  LA Rams -7.0
Total: 
Over 49.5 

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