Connect with us

NCAA FB

Ole Miss vs Tulane CFP Odds, Pick and Prediction

Ole Miss hosts Tulane in a CFP first round showdown with big spread implications and total analysis.

2025 College Football Playoff - Tulane vs Ole Miss
  • This page contains affiliate links. We may earn a commission at no extra cost to you.

Tulane (11-2) at Ole Miss (11-1)

  • When: Dec 20 2025, 3:30 PM
  • Where: Vaught-Hemingway Stadium, Oxford, MS
  • Where to watch: TNT
  • Last Meeting: Ole Miss 45-10, September 20th, 2025

(20) Tulane vs (6) Ole Miss Preview & Prediction

Spread: Ole Miss -17.0
Moneyline: Ole Miss (-800)
Total: 58.0

Ole Miss Rebels Outlook

Ole Miss enters this playoff opener as a heavy favorite and with plenty of intrigue on the sideline. The Rebels sit at 11 and 1 and are transitioning into a new era after elevating defensive coordinator Pete Golding to head coach. While the headset is new, the foundation is not. Golding keeps continuity on defense and retains Charlie Weis Jr. to run the offense, which should limit any disruption.

Offensively, Ole Miss remains explosive. The Rebels score over 37 points per game and thrive on tempo, balance, and quarterback confidence. Trinidad Chambliss is coming off an elite season and already torched Tulane earlier this year in Oxford with both his arm and legs. That familiarity matters in a playoff setting. The Rebels also bring a physical edge at home, where they have overwhelmed opponents all season. Laying a large number is never comfortable in the postseason, but Ole Miss has shown it can separate quickly when it gets rolling.

Tulane Green Wave Outlook

Tulane arrives with momentum but also with pressure. This could be the final game under Jon Sumrall, who is finishing out the season before moving on. The Green Wave went 11 and 2 and bounced back from late season adversity with a conference title win, proving they still have fight.

The challenge is consistency. Tulane averages just under 30 points per game and struggled badly against Ole Miss earlier this season, especially at quarterback. Jake Retzlaff is more settled now after a full year in the system, but this is a massive jump in competition. Tulane may need to lean on long drives and special teams to stay within striking distance. If they stall in the red zone again, field goals will not be enough against an offense like this.

Betting Outlook and Prediction

Ole Miss has the matchup edge, the home crowd, and the offensive ceiling. Tulane is well coached and tougher than the first meeting showed, but asking them to win outright feels like a reach. The question is margin. With playoff urgency and an offense built to stretch leads, Ole Miss has a clear path to covering if it plays clean football.

Final Score: Ole Miss 41, Tulane 20
Lean: Ole Miss -17.0
Total: 
Over 58.0 

2026 CFP National Championship

Click to comment

Leave a Reply

Your email address will not be published. Required fields are marked *

Top Sportsbooks

bovada logo
75% Welcome Bonus up to $750
betonline
50% Welcome Bonus Up to $1000
mybookie
100% Welcome Bonus up to $1,000
365betting
Weekly Promotions & Much More

More in NCAA FB