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Tulane (11-2) at Ole Miss (11-1)
- When: Dec 20 2025, 3:30 PM
- Where: Vaught-Hemingway Stadium, Oxford, MS
- Where to watch: TNT
- Last Meeting: Ole Miss 45-10, September 20th, 2025
(20) Tulane vs (6) Ole Miss Preview & Prediction
Spread: Ole Miss -17.0
Moneyline: Ole Miss (-800)
Total: 58.0
Ole Miss Rebels Outlook
Ole Miss enters this playoff opener as a heavy favorite and with plenty of intrigue on the sideline. The Rebels sit at 11 and 1 and are transitioning into a new era after elevating defensive coordinator Pete Golding to head coach. While the headset is new, the foundation is not. Golding keeps continuity on defense and retains Charlie Weis Jr. to run the offense, which should limit any disruption.
Offensively, Ole Miss remains explosive. The Rebels score over 37 points per game and thrive on tempo, balance, and quarterback confidence. Trinidad Chambliss is coming off an elite season and already torched Tulane earlier this year in Oxford with both his arm and legs. That familiarity matters in a playoff setting. The Rebels also bring a physical edge at home, where they have overwhelmed opponents all season. Laying a large number is never comfortable in the postseason, but Ole Miss has shown it can separate quickly when it gets rolling.
Tulane Green Wave Outlook
Tulane arrives with momentum but also with pressure. This could be the final game under Jon Sumrall, who is finishing out the season before moving on. The Green Wave went 11 and 2 and bounced back from late season adversity with a conference title win, proving they still have fight.
The challenge is consistency. Tulane averages just under 30 points per game and struggled badly against Ole Miss earlier this season, especially at quarterback. Jake Retzlaff is more settled now after a full year in the system, but this is a massive jump in competition. Tulane may need to lean on long drives and special teams to stay within striking distance. If they stall in the red zone again, field goals will not be enough against an offense like this.
Betting Outlook and Prediction
Ole Miss has the matchup edge, the home crowd, and the offensive ceiling. Tulane is well coached and tougher than the first meeting showed, but asking them to win outright feels like a reach. The question is margin. With playoff urgency and an offense built to stretch leads, Ole Miss has a clear path to covering if it plays clean football.
Final Score: Ole Miss 41, Tulane 20
Lean: Ole Miss -17.0
Total: Over 58.0
- NCAA Football Odds source: Bovada Sportsbook
- Get real-time live scores & latest betting odds here!