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UConn (11-1) vs DePaul (8-4)
- When: Dec 21 2025, 4:30 PM
- Where: Wintrust Arena, Chicago, IL, USA
- Where to watch: Fox Sports 1
(5) UConn vs DePaul Preview & Prediction
Spread: UConn -15.0
Moneyline: UConn (-1600)
Total: 137.0
UConn Huskies Betting Breakdown
UConn continues to look like a national title contender as Big East play ramps up. After spending most of the nonconference slate at home, the Huskies now hit the road for a conference matchup in Chicago carrying an 11-1 record and early momentum in league play.
Their Big East opener was not perfect, but it was dominant where it mattered. UConn shook off a sluggish start and overwhelmed Butler with size, defense, and physicality. Once the Huskies settled in, they controlled the glass, erased shots at the rim, and turned a competitive game into a comfortable win. That ability to flip the switch remains one of UConn’s biggest strengths.
Offensively, the Huskies are balanced and difficult to scheme against. Solo Ball has emerged as the leading scorer and continues to stretch defenses, while the supporting cast does a strong job creating opportunities and sharing the ball. UConn’s depth and rebounding edge often lead to second-half separation, especially against teams that cannot match their size.
UConn has also dominated this matchup historically and enters as a heavy road favorite at minus 15.0. The expectation is not just to win, but to assert control early and avoid another slow start that could keep an inferior opponent hanging around.
DePaul Blue Demons Betting Breakdown
DePaul opened conference play with a loss but showed enough fight to suggest it will not roll over at home. The Blue Demons hung around in the second half against St. John’s before talent and depth eventually took over.
Kaleb Banks delivered one of his best performances of the season, providing scoring, rebounding, and energy on both ends. CJ Gunn remains DePaul’s primary offensive threat and has been consistent scoring the basketball over the last several games. Together, they give DePaul enough offense to avoid getting completely shut down.
That said, DePaul faces a major step up in class. Rebounding has been an issue against elite opponents, and UConn’s physical presence inside poses a serious problem. If the Blue Demons cannot keep this game at a manageable pace, it could get out of hand quickly.
DePaul’s best chance is to slow the tempo, hit timely shots, and hope UConn does not bring its best defensive intensity for a full forty minutes.
Prediction and Betting Outlook
DePaul should show some resistance early, especially at home, but UConn’s size, depth, and defensive pressure are likely to wear the Blue Demons down after halftime.
This sets up as a game where the Huskies gradually pull away rather than blow it open immediately. Expect UConn to control the boards, limit easy looks, and build a steady lead in the final ten minutes.
Final Score: UConn 76, DePaul 60
Lean: UConn -15.0
Total: Under 137.0
- NCAAB Odds source: Bovada Sportsbook
