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Arizona State (1-0) at Mississippi State (1-0)
- When: Sep 6 2025, 7:30 PM
- Where: Davis Wade Stadium at Scott Field, Starkville, MS
- Where to watch: ESPN2
- Last Meeting: Arizona State 30-23, September 7th, 2024
(12) Arizona State vs Mississippi State Preview & Prediction
Spread: Arizona State -6.5
Moneyline: Arizona State -244
Total: 59.0
Arizona State Sun Devils Betting Outlook
The Sun Devils walk into Starkville looking to make it two straight against SEC opposition. Last year’s 30-23 victory over Mississippi State was built on pure trench dominance, 346 rushing yards and more than 40 minutes of possession. That formula travels well, but so does the pressure.
Arizona State opened its season with a 38-19 win over Northern Arizona, though the performance wasn’t quite as clean as the scoreboard suggests. Twelve penalties and a woeful 1-for-10 mark on third down had coach Ken Dillingham openly admitting he was outcoached.
Quarterback Sam Leavitt was still dynamic, tallying four touchdowns (two passing, two rushing) while racking up 330 combined yards. His chemistry with Jordyn Tyson (12 catches, 141 yards, two TDs) gives the Sun Devils a reliable passing punch to complement their ground game. If Arizona State cleans up discipline, their edge in talent should shine.
Mississippi State Bulldogs Betting Outlook
The Bulldogs started 2025 by taking care of business against Southern Miss in a 34-17 win, fueled by quarterback Blake Shapen’s return from injury. Shapen looked sharp, completing 26-of-33 passes for 272 yards with one touchdown. More importantly, he led three scoring drives in the third quarter to break the game open.
It’s a stark contrast from last season, when Mississippi State collapsed to a 2-10 record after Shapen’s early injury. Against Arizona State last year, he threw for 268 yards and two scores, and he’ll need a similar performance to keep the Bulldogs competitive against a ranked foe.
The Bulldogs’ defense was opportunistic last week, but facing Arizona State’s balance of run and pass is a different beast. With the infamous cowbells of Starkville behind them, Mississippi State hopes to make this a shootout and ride Shapen’s arm to an upset bid.
Prediction & Betting Angle
This game boils down to whether Mississippi State’s passing attack can crack Arizona State’s defense, and whether the Sun Devils can avoid the sloppy mistakes that plagued their opener. The cowbells may rattle, but the Sun Devils have more firepower.
Final Score: Arizona State 34, Mississippi State 24
Lean: Arizona State -6.5
Total: Over 59.0 – both teams have enough offensive pop to push this past the number.
- NCAA Football Odds source: Bovada Sportsbook
- Get real-time live scores & latest betting odds here!
