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Orioles vs Giants Betting Preview, Odds & Prediction

Expert Orioles vs Giants betting breakdown with moneyline odds, total, and prediction for Saturday’s matchup.

(Photo by Getty Images) Trevor Rogers
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Baltimore (60-75) at San Francisco (67-68)

  • When: Aug 30 2025, 7:15 PM
  • Where: Oracle Park, San Francisco
  • Where to watch: FOX

Orioles vs. Giants – Game Betting Preview & Prediction

Moneyline: Baltimore -128 
Spread: Baltimore -1.5 (+141)
Total: 8.0

Baltimore Orioles Betting Outlook

The Orioles will send Trevor Rogers to the mound on Saturday, and few pitchers have been hotter across the league. Rogers enters with a 7-2 record and a sparkling 1.40 ERA, allowing just four runs over his last 27 innings while leading Baltimore to four consecutive wins in his starts. He’s been remarkably consistent, surrendering more than two runs in just one of his 13 outings this season.

Despite his dominance, Baltimore has struggled as a team, dropping eight of their last nine games. The lone bright spot during that skid came in Rogers’ most recent start, a 3-2 victory over Houston. Offensively, Ryan Mountcastle and Coby Mayo provided some punch in Friday’s loss, with Mountcastle driving in four runs and Mayo homering, but the lineup has been inconsistent. For Baltimore to cash in as the road favorite, Rogers will likely need to continue carrying the load.

San Francisco Giants Betting Outlook

The Giants answered Baltimore’s ace with a thunderous offensive display in the series opener, erupting for 18 hits and 15 runs in a 15-8 rout. Every starter in the lineup recorded a hit, eight different players crossed the plate, and six drove in runs. Willy Adames paced the attack with four hits, showing the renewed spark of a club that has flipped the script after being one of the lowest-scoring teams in baseball for much of the season.

San Francisco enters Saturday on a six-game winning streak, averaging 7.8 runs during that stretch while batting .307 as a team with 12 home runs. Carson Seymour will make his first major league start after 10 bullpen appearances. He worked primarily as a starter in Triple-A earlier this year and posted respectable numbers, but this assignment against a pitcher of Rogers’ caliber will be a tough introduction.

MLB Final Betting Outlook & Prediction

MyBookie Oddsmakers list Baltimore as the moneyline favorite at -128, with the total set at 8.0 runs. Bettors face a classic clash between a dominant starting pitcher and a red-hot offense. Rogers has been lights out, but San Francisco’s bats are on fire, and Friday’s eruption showed the Giants can get to quality pitching when they’re locked in.

The edge still leans toward Baltimore given Rogers’ elite form, but San Francisco’s momentum and home-field confidence make this matchup far from a sure thing. The total at 8.0 feels tight, hinging on whether the Orioles can offer Rogers the run support he needs.

Score Prediction: Orioles 5, Giants 3
Pick: Baltimore (-128)
Total: Over 7.5 Alt Lines (-125) 

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