Baltimore (0-0) at Toronto (0-0)
- When: Mar 27 2025, 3:07 PM
- Where: Rogers Centre, Toronto
- Where to watch: CTV Sportsnet
MLB Expert Breakdown: Blue Jays vs Orioles – Betting Preview, Odds & Predictions
Moneyline: Baltimore Orioles -112 | Total: 8.5 Runs
Toronto Blue Jays (Home)
The Blue Jays begin their 2025 campaign with home-field advantage for the first time in three years. After finishing last in the AL East in 2024, this season is all about redemption—and they’ll get an early test against a familiar division rival.
Toronto looked sharp in spring training, boasting the best Grapefruit League record (18-10), including a dominant 14-1 at home. That momentum may give them a quick-start edge.
Veteran right-hander Jose Berrios takes the mound, coming off a strong 16-11 season with a 3.60 ERA. Berrios has owned the Orioles in his career, going 10-1 with a 2.95 ERA in 16 starts. With his command on point this spring, he’ll be a key factor in Toronto’s ability to control this opener.
Offensively, Vladimir Guerrero Jr. anchors a lineup that adds power with former Oriole Anthony Santander, who blasted a career-high 44 home runs last year. Look for Bo Bichette to bounce back after a frustrating, injury-riddled season. The additions of Andres Gimenez and Jeff Hoffman (slated to close) also bolster Toronto’s lineup and bullpen.
Player Prop Picks:
Vladimir Guerrero Jr. Over 1.5 total bases
Jose Berrios Over 5.5 strikeouts
Baltimore Orioles (Away)
Baltimore has posted back-to-back postseason appearances but still hasn’t secured a playoff win in that stretch. This season, they’re aiming for more than just October entry.
The O’s will start Zach Eflin, who went 10-9 with a 3.59 ERA last year. However, he’s had mixed results vs. Toronto—posting a 5.72 ERA across nine career appearances. That’s a concern against a loaded Jays lineup with power from both sides.
Baltimore is already dealing with injuries. Gunnar Henderson (2024 Rookie of the Year candidate) starts the season on the IL, and a big part of their rotation—including Kyle Bradish and Grayson Rodriguez—will also miss time. That leaves the pressure on Eflin and bullpen returnee Felix Bautista to anchor things early.
Tyler O’Neill was brought in to add pop to the offense, and Jackson Holliday could step up in Henderson’s absence, but the lineup looks thinner compared to Toronto’s depth—especially early on.
Player Prop Picks:
Tyler O’Neill Under 1.5 total bases
Zach Eflin Over 2.5 earned runs allowed
Prediction:
This one shapes up as a tight AL East clash, but the edge goes to the Blue Jays in the opener. Berrios’ dominance against Baltimore combined with Toronto’s spring momentum and more stable roster gives them the edge.
Best Bet: Blue Jays Moneyline (-108)
Prediction: Blue Jays 5, Orioles 3
Lean: Under 8.5 (-115) – with both starters capable of managing lineups early
- MLB Odds source: MYBookie Sportsbook
