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Guardians vs Mets MLB Baseball Odds & Parlay Picks

Cleveland and NY Mets will meet on the field at Citi Field in a battle of interleague teams.

(Photo by Getty Images) Sean Manaea
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Cleveland (56-55) at NY Mets (63-49)

  • When: Aug 4 2025, 7:10 PM
  • Where: Citi Field, Flushing, Queens
  • Where to watch: CLEG

Guardians vs. Mets – Game Betting Preview & Prediction

Moneyline: NY Mets -182 
Spread: NY Mets -1.5 (+115)
Total: 8.0

New York Mets Betting Preview

The Mets are leaning heavily on Sean Manaea Monday night as they try to stabilize a rotation that’s running on fumes. Manaea (1-1, 2.08 ERA) has been sharp in limited work this season, but he’s yet to pitch beyond five innings or exceed 86 pitches. With a battered bullpen and multiple starters still on pitch counts, the Mets need him to stretch out badly.

Injuries have gutted New York’s starting staff: Paul Blackburn, Griffin Canning, Tylor Megill, and Kodai Senga have all missed time. Montas was shelled in his last outing, and Saturday’s win came only after a bullpen effort bailed out another short start. Carlos Mendoza has been juggling arms like he’s at a Vegas act, and it’s catching up.

Offensively, the Mets were humbled in a 12-4 loss to San Francisco Sunday, a game where the early deficit proved too deep to climb out of. However, Manaea’s track record against the Guardians (3-1, 2.94 ERA across six starts) gives reason for optimism if he can finally pitch deep into the game.

Cleveland Guardians Betting Preview

Cleveland enters the series just three games out of an AL Wild Card spot, despite making some moves at the deadline that seemed to signal a soft sell. Gone are Shane Bieber and Paul Sewald, but the front office held onto key pieces like Steven Kwan and clubhouse leader Carlos Santana.

Even after a tough 5-4 loss to the Twins Sunday, the Guardians have been hot, 16-7 since July 7 and are getting production up and down the lineup. However, they’re without closer Emmanuel Clase and starter Luis Ortiz due to ongoing MLB gambling investigations, thinning an already fragile bullpen.

Slade Cecconi (5-7, 3.77 ERA) gets the nod Monday. He went seven innings with three earned runs his last time out and looks more comfortable every turn through the rotation. He faced the Mets once in 2024 and held them to a run across 4.2 innings, nothing flashy, but serviceable.

Prediction

The Mets are big favorites, but both teams come into this game dealing with rotation issues and some recent instability. Manaea’s ERA is elite, but his inability to pitch deep into games could put pressure on a tired bullpen. Cecconi is capable of keeping things close if the Guardians’ offense continues to produce.

Manaea does just enough, and the Mets’ lineup capitalizes on bullpen mismatches late. Lean under 8.0 in a game with potential early rhythm and late caution.

Score Prediction: Mets 4, Guardians 3
Pick:   Cleveland +1.5 (-136)
Total: Under 8.0 (-105)  

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