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Houston (84-74) at Athletics (75-83)
- When: Sep 25 2025, 3:35 PM
- Where: Sutter Health Park, West Sacramento
- Where to watch: SCHN
Astros vs. Athletics – Game Betting Preview & Prediction
Moneyline: Houston -114
Spread: Houston -1.5 (+140)
Total: 9.5
Houston Astros Betting Outlook
The Astros are clinging to postseason life, but the clock is ticking. A five-game skid has put them on the brink, and getting shut down by the Athletics in back-to-back games hasn’t helped their cause. Houston now trails Detroit for the final AL Wild Card spot, and because the Tigers own the tiebreaker, the Astros need to outplay them outright in the last four days.
Framber Valdez (12-11, 3.75 ERA) gets the ball in Thursday’s finale. Once a trusted ace, Valdez has struggled badly of late, going 0-4 with an 8.27 ERA in his last four outings. He did beat Athletics earlier this year and owns a strong career ERA (2.66) against them, but if his command wavers again, Houston could be in serious trouble.
The offense has gone missing at the worst possible time, scoring just once in the first two games of this series. Jose Altuve, usually their spark, has yet to solve J.T. Ginn. The Astros desperately need a turnaround to avoid missing the playoffs for the first time since 2016.
Athletics Betting Outlook
Athletics might be out of playoff contention, but they’re playing spoiler like it’s a full-time job. Winners of seven straight against Houston, the A’s have pounded the Astros by a combined score of 49-12 in that stretch. Shea Langeliers has been the headline act, slugging his 31st homer and going 4-for-4 in Wednesday’s shutout win.
J.T. Ginn (4-6, 4.57 ERA) takes the mound, and he’s been surprisingly sharp against Houston. He blanked them earlier this year over six innings and owns a 1.69 ERA in three career appearances against the Astros. Brent Rooker and Langeliers have both homered off Valdez in past matchups, adding to Athletics’ confidence heading into the finale.
The Athletics have thrived on frustrating Houston and would love to extend their dominance by sweeping this series.
MLB Betting Outlook & Prediction
The Astros are listed as slight -114 favorites, with the total set at 9.5. But trends say otherwise: Houston is ice cold, Valdez has been unreliable, and the A’s have had their number all year. Athletics’ spoiler role feels alive and well. The A’s finish off the sweep, leaving Houston’s playoff dreams gasping for air.
Score Prediction: Athletics 6, Astros 4
Pick: Athletics (-103)
Total: Over 9.5 (-106)
- MLB Odds source: MyBookie Sportsbook
- Get real-time live scores & latest betting odds here!
