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Astros vs Mariners MLB Baseball Odds & Expert Picks

The division rival Houston and Seattle are set to renew hostilities when they meet at T-Mobile Park.

(Photo by Getty Images) Luis Castillo
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Houston (56-40) at Seattle (51-45)

  • When: Jul 18 2025, 10:10 PM
  • Where: T-Mobile Park, Seattle
  • Where to watch: SCHN

Astros vs Mariners – Game Preview & Expert Predictions

Moneyline: Seattle -135
Total: 7.5
RunLine: Seattle -1.5 (+165)

Seattle Mariners Breakdown

The Mariners have been a rollercoaster lately, but when they’re hot, they’re dangerous. They recently swept the Tigers in Detroit, scoring a ridiculous 35 runs in three games, showcasing just how explosive this lineup can be when it clicks. That rebound came after a brutal collapse in New York, where they blew a five-run lead in the late innings, a reminder that consistency remains their biggest challenge.

Cal Raleigh has been the definition of a power bat, smacking 38 homers this season and even taking home the Home Run Derby crown. Meanwhile, Julio Rodriguez looks refreshed after sitting out the All-Star Game, going 6-for-12 with three bombs in Detroit. At T-Mobile Park, Seattle’s offense will need to stay sharp to keep pace with Houston.

Player Prop Pick (Mariners): Cal Raleigh Over 1.5 Total Bases – Raleigh’s power surge and current form make him a threat every time he steps to the plate.

Houston Astros Breakdown

The Astros stumbled heading into the break, dropping five of six at home against Cleveland and Texas. Still, at 16 games over .500 and holding a five-game lead in the AL West, Houston isn’t panicking. Manager Joe Espada and All-Star hurler Hunter Brown remain confident this team is still the best in the division.

Brandon Walter (1-2, 3.98 ERA) gets the ball Friday. While his win-loss record doesn’t sparkle, his last start was solid, two runs over six innings with seven strikeouts against Cleveland. This will be his first career meeting with Seattle, and his command will be tested against a power-heavy Mariners lineup.

Player Prop Pick (Astros): Jose Altuve to Record an RBI – Altuve has been Houston’s most reliable bat and should have opportunities against Seattle’s uncertain pitching plans.

Prediction & Betting Outlook

Seattle’s offense has found its groove, but Houston’s experience and Walter’s ability to keep hitters off-balance give the Astros a slight edge in a tight series opener. Expect a low-scoring, grind-it-out matchup where one big inning decides it.

Best Bet: Houston (+113)
ToralUnder 7.5 (-115)
Final Score Prediction:
 Astros 4, Mariners 3

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