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Blue Jays vs Astros Betting Preview & Prediction

Blue Jays and Astros collide in a key AL showdown. Read the full betting preview and game prediction.

(Photo by Getty Images) Shane Bieber
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Houston (78-66) at Toronto (82-61)

  • When: Sep 9 2025, 7:07 PM
  • Where: Rogers Centre, Toronto
  • Where to watch: SCHN

Astros vs. Blue Jays – Game Betting Preview & Prediction

Moneyline: Toronto -159 
Spread: Toronto -1.5 (+130)
Total: 8.0

Toronto Blue Jays Betting Outlook

The Blue Jays enter this matchup at 82-61, still holding the top spot in the AL East, but their cushion is slipping. After dropping a close 4-3 game to the Yankees on Sunday, their division lead is down to just two games. Toronto returns home following a 3-3 road trip and will play six straight at Rogers Centre, critical games with control of the division hanging in the balance.

Toronto turns to Shane Bieber (2-1, 4.15 ERA), who is working back from Tommy John surgery. In his last start, he allowed five runs in one rough inning but settled in afterward to secure the win. Bieber has pitched well historically against Houston, holding a 2.25 ERA across three career starts. With home field advantage and the division race tightening, Toronto needs a strong showing to fend off the surging Yankees.

Houston Astros Betting Outlook

Houston enters at 78-66, clinging to a 2.5-game lead in the AL West after losing two of three to Texas. The Astros have been inconsistent, going 3-6 in their last nine, and offensive struggles continue to be a concern—they managed just five hits in Sunday’s loss and were once again inefficient with runners in scoring position.

Luis Garcia (1-0, 4.50 ERA) gets the ball for his second start since returning from Tommy John surgery. Garcia has been sharp against Toronto in the past, owning a 2.88 ERA in four career outings. Houston also gets a boost with Jake Meyers returning to the lineup, giving them depth both defensively and at the bottom of the order. The Astros swept the Jays back in April and have won seven of the last eight meetings, which adds confidence despite recent struggles.

Betting Outlook & Prediction

The oddsmakers list Toronto as the -159 moneyline favorite, with the total set at 8.5 runs. The Blue Jays have steadier starting pitching right now, while Houston’s bats have cooled off at the wrong time. Toronto’s pitching edge and home-field momentum tilt this opener in their favor, though expect a competitive, high-leverage game.

Score Prediction: Blue Jays 5, Astros 4
Pick: Toronto (-159)
Total: Over 8.5 (-110) 

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