LA Angeles (8-5) at Houston (6-7)
- When: Apr 12 2025, 7:10 PM
- Where: Daikin Park, Houston
- Where to watch: FDSW
MLB Expert Breakdown & Predictions: Angels vs. Astros
Moneyline: Astros -155 | Total: 9.0
Houston Astros Outlook & Player Props
The Astros exploded offensively in the series opener against the Angels, piling up a season-high 14 runs in a rout. They got multi-hit efforts from six different starters, including standout games from Isaac Paredes and Yainer Diaz, both of whom homered and finished with three hits apiece. What truly defined the win, though, was Houston’s elite two-out execution — racking up nine two-out RBIs and turning what could’ve been short innings into extended damage.
Rookie Ryan Gusto will take the mound for his first MLB start after a sharp start to the season in relief (1.13 ERA over four appearances). He’s shown strong poise out of the bullpen, earning a win earlier this week in extra innings against Seattle. The right-hander led Triple-A in strikeouts last year and has serious upside.
Prop Targets
Isaac Paredes Over 1.5 Hits + Runs + RBIs – He’s heating up and batting with runners on base.
Yainer Diaz to Hit a Home Run (+ Odds) – Look for value after his Friday blast.
Ryan Gusto Over 3.5 Strikeouts – Solid strikeout pedigree, even as a starter.
Houston is playing with momentum and balance throughout the lineup. Their ability to extend innings makes them dangerous for betting overs on individual totals, and they have now scored 26 runs over their last three games.
Los Angeles Angels Outlook & Player Props
The Angels are stumbling through April, and Friday night’s blowout loss highlighted a recurring issue: lack of bullpen stability and inconsistent starting pitching. With Ben Joyce now shelved due to shoulder inflammation, the relief corps takes another hit. That puts even more pressure on Saturday’s starter Tyler Anderson, who’s had a historically tough time against the Astros (1-5, 6.43 ERA in 11 starts).
Anderson labored through five innings in his season debut, walking four and striking out five, while surrendering two earned runs. Against Houston’s hot bats, he’ll need pinpoint control — something that’s eluded him in past matchups.
Prop Targets
Mike Trout Over 1.5 Total Bases – If anyone’s due for impact in this lineup, it’s him.
Tyler Anderson Over 1.5 Walks – His command issues could surface against Houston’s patient hitters.
Offensively, Los Angeles will look to avoid falling behind early. They need stronger production from the middle of the order to compete in this one, and playing from behind has been a recurring problem.
Prediction & Best Bets
The Astros are rolling, and with Gusto stepping into the rotation with solid form, there’s plenty to like about Houston on their home turf. The Angels’ bullpen injuries and Anderson’s history against Houston create a lopsided matchup.
Best Bets:
Astros -1.5 Run Line (+135) – Houston’s lineup is clicking, and they’ve won 3 of their last 4 by 3+ runs.
Over 9.0 (-105) – The Astros could cover most of this themselves.
Ryan Gusto to Record a Win (+ Odds) – Value play with his recent form and favorable opponent.
Score Prediction: Astros 7, Angels 3
Houston should control the tempo early and coast to another series win behind another breakout night at the plate.
- MLB Odds source: MYBookie Sportsbook
