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San Francisco 49ers Host LA Rams in Rematch of NFC Title Game

The division rival Los Angeles Rams and San Francisco 49ers will meet on the field on Monday at Levi’s Stadium.

(Photo by Thearon W. Henderson/Getty Images) Jimmy Garoppolo

NFL Matchup: Los Angeles Rams @ San Francisco 49ers
When: 8:15 PM ET, Monday, October 3, 2022
Where: Levi’s Stadium, Santa Clara, California
Where to watch: ESPN

Los Angeles Rams @ San Francisco 49ers
Moneyline

Los Angeles Rams   EVEN
San Francisco 49ers   -120

Los Angeles Rams @ San Francisco 49ers
Point Spread

Los Angeles Rams   1.5 (-110)
San Francisco 49ers   -1.5 (-110)

Los Angeles Rams @ San Francisco 49ers
Total

Over   42.5 (-110)
Under   42.5 (-110)

Passing Team Leaders:
Los Angeles Rams: Matthew Stafford 761 Yds
San Francisco 49ers: Jimmy Garoppolo 365 Yds

by FLM

The San Francisco 49ers are seeking their seventh straight regular-season victory over the Los Angeles Rams, but they lost the game that mattered most last winter.

The teams will square off Monday night in Santa Clara, Calif., for the first time since Los Angeles defeated San Francisco in last season’s NFC Championship game. The Rams went on to beat the Cincinnati Bengals in Super Bowl LVI.

Los Angeles (2-1) also hasn’t beaten the 49ers (1-2) at Levi’s Stadium since 2018.

2025 Super Bowl LIX Odds

Betting Odds Trends

San Francisco 49ers
San Francisco is 6-2 ATS in its last 8 games
San Francisco is 10-5 SU in its last 15 games
The total has gone UNDER in 5 of San Francisco’s last 5 games
San Francisco is 5-0 ATS in its last 5 games at home
San Francisco is 5-0 SU in its last 5 games at home
The total has gone UNDER in 4 of San Francisco’s last 5 games at home
San Francisco is 5-0 ATS in its last 5 games when playing LA Rams
San Francisco is 6-1 SU in its last 7 games when playing LA Rams
The total has gone UNDER in 4 of San Francisco’s last 5 games when playing LA Rams
San Francisco is 5-2 ATS in its last 7 games when playing at home against LA Rams
San Francisco is 5-2 SU in its last 7 games when playing at home against LA Rams
The total has gone UNDER in 7 of San Francisco’s last 9 games when playing at home against LA Rams
Los Angeles Rams
LA Rams is 1-4 ATS in its last 5 games
LA Rams is 6-1 SU in its last 7 games
The total has gone UNDER in 4 of LA Rams’s last 5 games
LA Rams is 4-2 ATS in its last 6 games on the road
LA Rams is 5-0 SU in its last 5 games on the road
LA Rams is 0-5 ATS in its last 5 games when playing San Francisco
LA Rams is 1-6 SU in its last 7 games when playing San Francisco
The total has gone UNDER in 4 of LA Rams’s last 5 games when playing San Francisco
LA Rams is 2-5 ATS in its last 7 games when playing on the road against San Francisco
LA Rams is 3-10-1 SU in its last 14 games when playing on the road against San Francisco
The total has gone UNDER in 7 of LA Rams’s last 9 games when playing on the road against San Francisco

NFL Parlay Picks & Free Predictions

Final Score: LA Rams 23-17
The Pick: LA Rams (+100) & Under 42½
A $100 Parlay Bet will return $282 in Profit

NFL Odds source: Bovada Sportsbook

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