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Las Vegas (1-3-0) at Indianapolis (3-1-0)
- When: Oct 5 2025, 1:00 PM
- Where: Lucas Oil Stadium, Indianapolis, IN
- Where to watch: FOX
- Last Meeting: IND 23-20, December 31st, 2023
Las Vegas vs Indianapolis Preview & Prediction
Spread: Indianapolis -7.0
Moneyline: Indianapolis (-370)
Total: 48.0
Indianapolis Colts: Ground Game on a Mission
The Colts are rolling into Week 5 with momentum and a rushing attack that’s firing on all cylinders. Indianapolis sits at 3-1 and owns one of the league’s most balanced offensive approaches. At the heart of it all is Jonathan Taylor who continues to remind everyone why he’s one of the NFL’s elite workhorses.
Taylor currently leads the league in rushing yards and is top 6 in TDs, proving he’s still the engine of this Colts offense. While his stat sheet says he’s a beast, what you don’t see is the respect he gets from opposing defenses before the snap. Teams know he’s going to run, they just can’t stop him.
The Colts’ offensive line has held strong, and their defense has been opportunistic enough to back up Taylor’s production with wins. While Jalen Hurts and Lamar Jackson often get the dual-threat hype, Taylor quietly continues to punish teams in old-school fashion. Indy will look to exploit a Raiders front that’s been sturdy but vulnerable to explosive plays.
Why It Matters for Bettors: Indy has covered the spread in three straight games and looks like a team built to dominate physically. With Taylor leading the charge, and the Raiders reeling, laying the 7 points feels justifiable. This could get out of hand fast if Las Vegas can’t match the Colts in the trenches.
Las Vegas Raiders: Rookie Spotlight, But Growing Pains
The Raiders are a work-in-progress at 1-3, but not for lack of talent. Rookie running back Ashton Jeanty has been electric, leading all rookies in rushing yards and providing a rare bright spot in an otherwise inconsistent offense.
Jeanty’s unconventional upright stance before the snap? Yeah, it looks weird, but it works. He racked up over 130 yards last week, proving the Raiders may have struck gold. The problem? That gold is buried beneath a struggling offensive line and a lack of rhythm under center.
The loss of left tackle Kolton Miller only adds to the concern, especially now that Stone Forsythe steps in with big shoes to fill. Coach Pete Carroll and the staff are hoping Forsythe’s experience under their system pays off immediately but with the Colts’ pass rush looming, it’s going to be a trial by fire.
Las Vegas will also look to tight end Brock Bowers, who’s quietly on the verge of breaking a league record for consecutive games with at least two receptions to start a career. The offense may be young and inconsistent, but it isn’t lacking for raw talent.
Why It Matters for Bettors: The Raiders are trending in the wrong direction. Their inability to protect the quarterback and the pressure on a rookie running back to carry the load make them a risky play. A backdoor cover isn’t out of the question, but expect Indy to control tempo from the start.
Final Prediction:
Indianapolis controls the line of scrimmage, forces a turnover or two, and rides Taylor to a comfortable cover.
Final Score: Colts 30, Raiders 20
Lean: Indianapolis -7.0
Total: Over 48.0
- NFL Football Odds source: Bovada Sportsbook
- Get real-time live scores & latest betting odds here!