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Twins vs Tigers MLB Baseball Odds & Expert Picks

The division rival Minnesota and Detroit are set to renew hostilities when they meet at Comerica Park.

(Photo by Getty Images) Tarik Skubal

Minnesota (40-43) at Detroit (52-32)

  • When: Jun 29 2025, 7:10 PM
  • Where: Comerica Park, Detroit
  • Where to watch: ESPN

Twins vs Tigers – Game Preview, Prediction and Player Props

Moneyline: Detroit -265
Total: 7.5
RunLine: Detroit -1.5 (-125)

Detroit Tigers Outlook

The Tigers are rolling into Sunday night with their ace Tarik Skubal on the mound and betting against him at home has been pure bankroll sabotage this year. Skubal (9-2, 2.29 ERA) is a perfect 7-0 at Comerica Park with a stingy 2.30 ERA across those starts. The man flat-out deals in front of the home crowd.

He’s coming off a start where he spotted Oakland four runs early, then slammed the door shut the next four innings while his teammates mashed their way to an 11-4 comeback win. That kind of bounce-back mentality is exactly why Skubal’s a Cy Young front-runner again and nearly a lock to start the All-Star Game.

Prop Picks (DET)

Tarik Skubal Over 6.5 Strikeouts – He’s been striking out batters at will, and the Twins whiff often.
Zach McKinstry to Record a Hit – Quietly heating up, McKinstry has reached base safely in six of his last eight.

Minnesota Twins Outlook

Chris Paddack takes the ball for the Twins and… well, he might need a prayer circle. The right-hander (3-6, 4.64 ERA) has been lit up lately, allowing 18 earned runs in his last four starts. He gave up a five-spot in one inning vs. Seattle in his last outing and has looked rattled under pressure.

That said, he did pitch decently against Detroit earlier this season, but with how the Tigers have been swinging the bats, especially after crushing four homers on Saturday, he’s facing a steep climb.

Prop Picks (MIN)

Chris Paddack Over 1.5 Walks Allowed – Struggling with control in recent outings, especially late in games.
Byron Buxton to Score a Run – If the Twins find any offensive rhythm, it likely starts with Buxton creating chaos on the basepaths.

Betting Outlook

Detroit wins comfortably with another strong Skubal outing. Paddack gets chased early, and the Twins’ bullpen can’t keep it close. Detroit flexes their pitching and power edge to take the series.

Final Score Prediction: Tigers 6, Twins 2
Lean: Detroit RL -1.5 (-125)
Total: 
Over 7.5 (+100) 

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