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Twins vs Dodgers MLB Baseball Odds & Expert Picks

Minnesota and LA Dodgers will meet on the field at Dodger Stadium in a battle of interleague teams.

(Photo by Getty Images) Shohei Ohtani
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Minnesota (48-51) at LA Dodgers (58-42)

  • When: Jul 21 2025, 10:10 PM
  • Where: Dodger Stadium, Los Angeles
  • Where to watch: SportsNet LA

Twins vs Dodgers – Game Preview & Expert Predictions

Moneyline: LA Dodgers -195
Total: 9.0
RunLine: LA Dodgers -1.5 (-105)

Los Angeles Dodgers Breakdown

The Dodgers are looking for answers after dropping 10 of their last 12 games, including being swept by the Brewers twice in under two weeks. The skid includes six straight home losses, their longest home drought since 2017.

Shohei Ohtani will take the mound as Los Angeles attempts to right the ship. Ohtani (0-0, 1.00 ERA) continues his carefully monitored return to starting duty following Tommy John revision surgery, with plans to pitch three innings before handing the ball to Dustin May. Beyond his pitching, Ohtani remains a force at the plate, launching a two-run homer Sunday to highlight his dual-threat capability. He’s batting .301 with six homers and 14 RBIs in 24 career games against Minnesota.

Manager Dave Roberts also made a notable lineup adjustment, pushing a struggling Mookie Betts back to the leadoff spot, while Ohtani now bats second. Betts, who’s hitting just .195 over his last 21 games, will need to spark the offense early if the Dodgers hope to stop their slide.

Player Prop Pick – Dodgers: Shohei Ohtani to Record 2+ Total Bases – Ohtani’s bat is heating up, and he’s historically crushed Twins pitching.

Minnesota Twins Breakdown

Minnesota avoided a sweep in Colorado on Sunday with a dominant 7-1 win, fueled by a power surge that saw Royce Lewis blast two home runs, the first multi-homer game of his career. Lewis, a Southern California native, will be highly motivated to put on a show back home.

The Twins will send David Festa (3-3, 5.25 ERA) to the mound for his first career start against Los Angeles. Festa has settled into a better rhythm, winning two of his last three starts after a rough early stretch. However, facing Ohtani and a Dodgers lineup desperate to rebound will be his toughest test yet.

Player Prop Pick – Twins: Royce Lewis to Record a Hit – Lewis has been red-hot and thrives in high-pressure matchups.

Prediction & Betting Outlook

The Dodgers’ losing streak adds drama, but Ohtani’s presence on the mound and at the plate gives Los Angeles a clear edge. Expect Festa to battle, but the Dodgers should do just enough to claim a tight opener.

Best Bet: LA Dodgers -1.5 (-105)
ToralOver 9.0 (-105)
Final Score Prediction:
 Dodgers 6, Twins 4

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