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Yankees vs Reds MLB Baseball Odds & Parlay Picks

NY Yankees and Cincinnati will meet on the field at Great American Ball Park in a battle of interleague teams.

(Photo by Getty Images) Nick Lodolo

NY Yankees (45-32) at Cincinnati (40-38)

  • When: Jun 23 2025, 7:10 PM
  • Where: Great American Ball Park, Cincinnati
  • Where to watch: YES

Yankees vs. Reds – Game Betting Preview & Prediction

Moneyline: NY Yankees -123 | Total: 10.0

New York Yankees Betting Preview

The Yankees head to Cincinnati with a chip on their pinstriped shoulders. After getting swept by the Reds at home last July, New York now looks to return the favor on the road. They’ve steadied the ship lately, winning three of their last four after a six-game freefall.

But the injury bug hasn’t been kind. With Gerrit Cole, Marcus Stroman, Luis Gil, and now Ryan Yarbrough all on the IL, pitching depth has been stress-tested. Enter Allan Winans, freshly called up from Triple-A, where he’s been lights-out. The righty posted a jaw-dropping 0.90 ERA in 50 innings for Scranton/Wilkes-Barre and will now get the ball Monday night in his Yankees debut.

The Yankees’ offense, led by Aaron Judge and Juan Soto, remains lethal, and despite the injuries, they’re still positioned to take control of this series early, especially if Winans can bring his minor-league dominance to the show. Expect a hungry Bronx squad ready to take advantage of a Reds team that’s still inconsistent despite recent improvement.

Cincinnati Reds Betting Preview

Cincinnati avoided a weekend sweep with a 4-1 win over the Cardinals and enters this series having won 10 of their last 15. The offense has shown flashes, and Matt McLain is red-hot, riding a 10-game hitting streak into this one. If the bats stay warm, they’ll make life tough for Winans, especially in his Yankee debut under pressure.

Nick Lodolo will toe the rubber for the Reds. The left-hander has been solid, logging nine quality starts this season and coming off a rain-shortened complete-game win against Minnesota. Though he’s never faced the Yankees, Lodolo’s command and strikeout potential give Cincy a fighting chance, especially if their bullpen, which has been quietly reliable, can hold up in the later innings.

Prediction:

This one comes down to how well Winans handles the pressure of his first start. If the Yankees offense gets going early, they could overwhelm Lodolo. But don’t sleep on a scrappy Reds team that’s been finding ways to win.

Score Prediction: Yankees 6, Reds 5
Pick: NY Yankees ML (-123)
Total: Over 10.0 (-109) – in hitter-friendly Great American Ball Park

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