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Phillies vs Astros MLB Baseball Odds & Parlay Picks

Philadelphia and Houston will meet on the field at Houston Astros in a battle of interleague teams.

(Photo by Getty Images) Framber Valdez

Philadelphia (47-31) at Houston (45-33)

  • When: Jun 24 2025, 8:10 PM
  • Where: Houston Astros, Houston
  • Where to watch: NBCS-PH

Phillies vs. Astros – Game Betting Preview & Prediction

Moneyline: Houston -150 | Total: 7.5

Houston Astros Betting Preview

Houston limp into this six-game homestand missing several regulars, yet they keep climbing the AL ladder. After squeezing past the Angels 8-7 on Sunday, the Astros have captured seven of their last nine series (two ended in splits).

The spark plug? Jeremy Peña. The shortstop is scorching June pitching with a .381/.416/.536 slash, piling up four multi-hit outings in his last five starts. His two-way impact (4.5 WAR) has teammates openly stumping for an All-Star start and maybe even fringe MVP chatter.

Left-hander Framber Valdez (8-4, 3.09 ERA) draws Tuesday’s nod. Valdez hasn’t tasted defeat in eight straight outings, rolling up a 7-0 mark with a 2.13 ERA and 62 K in 55 innings. He walked five in Oakland last time out but still logged a comfortable win. Lifetime vs. Philadelphia: 1-1, 2.25 ERA (seven frames, three runs in their 2023 clash).

Philadelphia Phillies Betting Preview

The Phillies arrive fresh off a statement 7-1 win over the Mets, completing a divisional series victory and flipping a five-game deficit (June 11) into a one-game NL East lead. Rob Thomson’s club has shaken off its early-June wobble by winning 10 of 13.

Southpaw Ranger Suárez (6-1, 2.20 ERA) matches Valdez lefty-for-lefty. Suárez is locked in: eight straight quality starts and a stingy 0.91 ERA over his last six. His lone stumble against Houston came back in 2022 (six runs in three innings), but his current formband razor-sharp 4 BB over 27 June frames, suggest a very different outing this time around.

Prediction:

Valdez’s ground-ball wizardry meets Suárez’s groove in what profiles as a pitchers’ duel. Houston’s bats have been the hotter unit, yet Philadelphia’s bullpen has steadied lately. Lean on the home side’s momentum, but expect runs to be at a premium.

Score Prediction: Astros 4, Phillies 3
Pick: Houston ML (-150)
Total: Under 7.5 (-120) 

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