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Phillies vs Dodgers Odds, Expert Pick & Betting Preview

Expert handicappers break down Phillies vs Dodgers odds, pitching matchup, and score prediction for Wednesday night’s showdown.

(Photo by Getty Images) Blake Snell
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Philadelphia (91-61) at LA Dodgers (84-67)

  • When: Sep 17 2025, 10:10 PM
  • Where: Dodger Stadium, Los Angeles
  • Where to watch: NBCS-PH

Phillies vs Dodgers – Game Preview, Prediction and Player Props

Moneyline: LA Dodgers -149
Total: 8.0
RunLine: LA Dodgers -1.5 (+140)

Philadelphia Phillies Betting Outlook

The Phillies are proving why they’re one of the most dangerous lineups in baseball right now. After clinching the NL East, they’ve kept the pedal down by hammering Los Angeles’ bullpen in back-to-back games. That resilience even after being down four runs Tuesday speaks to a team built for October.

Jesús Luzardo gets the call, fresh off his best outing of the year where he went eight innings and fanned ten Mets. Historically, he’s had success against L.A., including a dominant seven-inning, two-hit performance earlier this season. His ability to attack with swing-and-miss stuff is a real problem for the Dodgers’ right-handed bats.

Phillies Player Prop Pick: Rafael Marchan to Record 2+ Total Bases. With Realmuto sidelined, Marchan is taking advantage of his opportunity and could deliver again in a sneaky spot.

Los Angeles Dodgers Betting Outlook

For L.A., the narrative is simple: the bats are producing, but the bullpen has been a ticking time bomb. Shohei Ohtani gave them five no-hit innings Tuesday and even clubbed his 50th home run, but the bullpen imploded again. With a 4.30 ERA on the season, relief pitching remains their biggest liability.

Blake Snell takes the mound trying to steady things. While his overall form (2.79 ERA) has been solid, his history against Philadelphia is ugly, 0-3 with a 4.28 ERA in six career starts. The Dodgers need him to finally flip that script if they want to avoid a sweep.

Dodgers Player Prop Pick: Shohei Ohtani to Hit a Home Run. He’s already smashed his way into history with back-to-back 50-homer seasons and still looks locked in at the plate.

MLB Prediction & Betting Angle

The Dodgers are -147 favorites with the total set at 8.0. But momentum is firmly on Philadelphia’s side, and Luzardo’s recent dominance gives them an edge. Expect a close battle, but another late push by the Phillies feels likely.

Final Score Prediction: Phillies 5, Dodgers 4
Lean: Philadelphia (+124)
Total: 
Over 8.0 (-104) 

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