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Philadelphia (3-0-0) at Tampa Bay (3-0-0)
- When: Sep 28 2025, 1:00 PM
- Where: Raymond James Stadium, Tampa, FL
- Where to watch: FOX
- Last Meeting: TB 33-16, September 29th, 2024
Philadelphia vs Tampa Bay Preview & Prediction
Spread: Philadelphia -3.5
Moneyline: Philadelphia (-185)
Total: 44.0
Philadelphia Eagles Betting Outlook
Philadelphia enters this matchup as a 3.5-point road favorite, and for good reason. The Eagles are 19-1 since their last trip to Tampa, a run that has defined one of the most dominant stretches in franchise history.
Last week, the Birds pulled off an improbable 33-26 comeback over the Rams, erasing a 19-point deficit behind Jalen Hurts’ second-half surge. Hurts tossed three touchdowns, while Jordan Davis sealed it with a blocked field goal return.
A.J. Brown finally broke loose with a 109-yard, one-score outing, and his presence changes the dynamic compared to prior matchups against Tampa. Saquon Barkley, however, is lagging behind his MVP-caliber pace from last year, averaging just 64.7 yards per game.
The key will be whether Philadelphia’s offense can dictate tempo and overcome Tampa’s tough run defense. If Hurts keeps finding Brown and Devonta Smith in rhythm, the Eagles have a clear path to victory.
Tampa Bay Buccaneers Betting Outlook
The Bucs may be home underdogs at +3.5, but they’ve shown a flair for the dramatic. Their 3-0 start, their best since 2005 has come by a razor-thin combined margin of six points. Baker Mayfield’s late-game heroics have carried Tampa, including last week’s last-second 29-27 win over the Jets.
Even without Mike Evans, this team remains dangerous. Chris Godwin and Tristan Wirfs are expected back, giving Mayfield more tools to attack Philly’s secondary. The defense is Tampa’s anchor, riding an 11-game streak without allowing a 100-yard rusher, and that could neutralize Barkley.
Todd Bowles’ unit thrives on discipline and situational defense, which will be essential against Hurts’ dual-threat ability.
Prediction & Betting Angle
Both teams have relied on narrow escapes early this season, but Philadelphia’s balance on both sides of the ball makes them the safer play. Tampa will battle in the trenches, but Hurts and the Eagles should pull away late.
Final Score: Eagles 27, Buccaneers 21
Lean: Philadelphia -3.5
Total: Over 44.0
- NFL Football Odds source: Bovada Sportsbook
- Get real-time live scores & latest betting odds here!
