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Padres vs Brewers MLB Baseball Odds & Expert Parlay Picks

San Diego and Milwaukee will both be trying to pick up a win when they battle at American Family Field.

(Photo by Getty Images) Jose Quintana

San Diego (36-26) at Milwaukee (34-30)

  • When: Jun 7 2025, 7:35 PM
  • Where: American Family Field, Milwaukee
  • Where to watch: FOX

Padres vs Brewers – Game Preview, Prediction and Player Props

Moneyline: Milwaukee -118 | Total: 8.5

San Diego Padres Preview

The Padres edged out a tight 2-0 win in Friday’s opener, thanks in large part to Manny Machado’s continued power surge. He launched his ninth homer of the season, his third in the last eight games on an 0-2 pitch in the eighth to seal the game. While San Diego isn’t exactly crushing the ball (only three homers in their last eight games), Machado has been the exception and a key offensive contributor, logging six homers and 12 RBIs in his last 14 appearances.

Right-hander Stephen Kolek (3-1, 3.47 ERA) will take the mound for the Padres. He’s been consistent, going at least five innings in all six starts and sporting a 1.04 ERA across four road outings. Ground-ball outs and steady defense behind him have been the formula for success.

Padres Prop Pick: Manny MachadoTo Record a Home Run

Milwaukee Brewers Preview

Milwaukee had its momentum halted in Friday’s shutout loss, going just 1-for-9 with runners in scoring position and leaving 10 men on base. Still, the Brewers have won 9 of their last 11 games and return to action behind Christian Yelich, who’s riding a red-hot 12-game hitting streak, hitting .423 with six homers during that stretch.

Veteran lefty Jose Quintana (4-1, 2.77 ERA) will start after a decent return from a shoulder injury, allowing two runs over five innings against Philly. He’s been solid vs. the Padres historically, including an 0.73 ERA across two outings last year.

Brewers Prop Pick: Christian YelichTo Record 2+ Total Bases

Prediction & Betting Outlook

Milwaukee should bounce back behind Quintana, but this has the makings of a low-scoring duel. Back the Under 8.5 and a tight Brewers win.

Final Score Prediction: Brewers 4, Padres 3
Lean: Milwaukee ML (-118)
Total: 
Under 8.5 (-110)

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