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Padres vs Phillies MLB Baseball Odds & Parlay Picks

Citizens Bank Park has a contest on tap as San Diego and Philadelphia will both be trying to pick up a win.

(Photo by Getty Images) Zack Wheeler

San Diego (45-38) at Philadelphia (49-35)

  • When: Jun 30 2025, 6:30 PM
  • Where: Citizens Bank Park, Philadelphia
  • Where to watch: NBCS-PH

Padres vs. Phillies – Game Betting Preview & Prediction

Moneyline: Philadelphia -222 | Total: 9.0

Philadelphia Phillies Preview

The Phillies roll into this matchup with a potential ace up their sleeve, literally. Bryce Harper might make his long-awaited return from a wrist injury that’s kept him sidelined since June 5. Even if he doesn’t start, the boost in energy could be real.

Zack Wheeler (7-3, 2.45 ERA) gets the ball, and he’s been untouchable lately, holding opponents to one earned run or fewer in seven of his last eight outings. Against the Padres, he owns a 4-1 record with a 2.06 ERA over nine starts. The bullpen, including arms like Kerkering and Strahm, continues to shut the door late in games.

The Phillies aren’t blowing teams away at the plate lately, but they’re doing enough to win, especially with Wheeler keeping the pressure off.

San Diego Padres Preview

The Padres are trying to shake off a brutal Sunday collapse, where closer Robert Suarez got tagged in a 3-2 loss to the Reds. That made it 12 losses in their last 15 games and added questions to a once-reliable bullpen.

Matt Waldron takes the mound for San Diego after a long injury layoff. He’s 1-0 with a 3.09 ERA in two career appearances against Philly and had one of his best 2024 starts at Citizens Bank Park earlier this season. But rust, pressure, and a confident Philly side could be too much for the knuckleballer to overcome.

Unless the Padres can wake up offensively, it could be another quiet night for the West Coast crew.

Prediction & Betting Picks

Zack Wheeler continues his dominant run, Bryce Harper injects life whether he plays or not, and the Phillies take control behind steady pitching and timely offense.

Score Prediction: Phillies 5, Padres 2
Pick: Philadelphia RL -1.5 (-105)
Total: Under 9.0 (-112) 

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