San Diego (35-24) at San Francisco (33-28)
- When: Jun 4 2025, 9:45 PM
- Where: Oracle Park, San Francisco
- Where to watch: SDPA
Padres vs Giants – Game Preview, Prediction and Player Props
Moneyline: San Diego -115 | Total: 7.0
San Diego Padres Overview
The Padres enter Wednesday night riding a three-game win streak, including two straight on the road, and are eyeing a season sweep over their division rivals. They’re sending Nick Pivetta (6-2, 2.74 ERA) to the mound, who’s in form with three straight solid starts. Over his last 18 innings, he’s held opponents to just four earned runs and has kept hitters in check with consistent strike throwing.
Pivetta has already beaten San Francisco this season, giving up three runs in 5 1/3 innings back in April. The Padres’ offense is finally getting timely production, including from Brandon Lockridge, a late-bloomer who had a two-hit night Tuesday and looks more comfortable at the plate with each game.
San Francisco Giants Breakdown
The Giants are struggling to support their stellar pitching. They’ve failed to score more than four runs in any of their last 16 games and have dropped four straight to San Diego. Kyle Harrison (1-1, 2.51 ERA) gets the start, and while his ERA looks sharp, he’s already served up six homers to the Padres across two starts, including bombs to stars like Tatis, Machado, and Bogaerts.
Even with prospects like Bryce Eldridge getting closer to their debut, the Giants’ offense remains stuck in neutral. Manager Bob Melvin is running out of patience as wasted gems from his starters pile up.
Top Props Picks
Nick Pivetta – Over 5.5 Strikeouts: With San Francisco’s bats ice-cold, Pivetta has a great shot to fan 6+ hitters.
Fernando Tatis Jr. – to Record a Hit: He’s previously homered off Harrison and is a consistent threat vs. lefties.
Betting Outlook & Prediction
The Padres’ balanced momentum and Pivetta’s rhythm give them the edge. Take San Diego on the moneyline and consider the under 7.0 in a pitcher-friendly matchup.
Final Score Prediction: Padres 4, Giants 2
Lean: San Diego ML (-115)
Total: Under 7.0 (-105)
San Diego keeps rolling while San Francisco’s offensive woes continue.
- MLB Odds source: MyBookie Sportsbook
- Get real-time live scores & latest betting odds here!
