- This page contains affiliate links. We may earn a commission at no extra cost to you.
San Diego (66-52) at San Francisco (59-59)
- When: Aug 11 2025, 9:45 PM
- Where: Oracle Park, San Francisco
- Where to watch: NBCS-BA
Padres vs Giants – Game Preview, Prediction and Player Props
Moneyline: San Francisco -141
Total: 7.5
RunLine: San Francisco -1.5 (+135)
San Diego Padres Betting Outlook
The Padres roll into Oracle Park with a 66-52 record, comfortably holding the NL’s second Wild Card spot. Seven games ahead of the Giants in the standings, San Diego has a golden chance to bury their divisional rivals with a strong showing in this three-game set.
Yu Darvish (1-3, 6.51 ERA) has finally found some rhythm after a rough start to 2025. Over his last two outings, he’s given up just three runs across 11 innings, helping the Padres secure wins against both the Mets and Diamondbacks. His veteran presence on the mound is invaluable, but history hasn’t been kind to him in this matchup, Darvish owns a 2-3 record with a 5.89 ERA in 12 career starts versus San Francisco.
Player Prop to Watch: Fernando Tatis Jr. – Over 1.5 Total Bases. Tatis has shown consistent power against righties and could be the offensive spark San Diego needs.
San Francisco Giants Betting Outlook
The Giants (59-59) are four games back of the final Wild Card spot and in urgent need of a bounce-back after getting humiliated 8-0 by Washington on Sunday. Manager Bob Melvin openly called it the “most disappointing game” of the season, a clear call-out to his team’s lackluster performance.
Logan Webb (10-8, 3.24 ERA) gets the ball, and if anyone can stop the bleeding, it’s him. Webb has been solid against San Diego in his career, sporting a 2.98 ERA over 16 appearances. Earlier this season, he threw eight shutout innings against the Padres but walked away with a no-decision in a 1-0 extra-inning loss.
Player Prop to Watch: Heliot Ramos – To Record a Hit. Ramos has been a bright spot in San Francisco’s lineup, bringing both power and contact ability in key spots.
Prediction & Betting Angle
If Darvish maintains his recent form, the Padres could steal this one, but their offense will need early run support against Webb. Webb should keep the game tight, and given the Giants’ urgency at home, the value leans toward San Francisco in a low-scoring grind.
Final Score Prediction: Giants 4, Padres 3
Lean: San Francisco (-141)
Total: Under 7.5 (-108)
- MLB Odds source: MyBookie Sportsbook
- Get real-time live scores & latest betting odds here!
