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San Diego (68-52) at San Francisco (59-61)
- When: Aug 13 2025, 3:45 PM
- Where: Oracle Park, San Francisco
- Where to watch: NBCS-BA
Padres vs. Giants – Game Betting Preview & Prediction
Moneyline: San Diego -161
Spread: San Diego -1.5 (+107)
Total: 8.0
San Diego Padres Betting Preview
San Diego heads into Wednesday’s matinee with a chance to finish off a three-game sweep in San Francisco and possibly grab sole possession of first place in the NL West, at least temporarily. After trailing the Dodgers by seven games and the Giants by one as recently as July 7, the Padres have caught fire, winning 20 of their last 30 to pull even with Los Angeles atop the division.
Their offense has been locked in during this series, racking up 10 hits in each of the first two matchups, both against San Francisco’s top arms, Logan Webb and Robbie Ray. Extra-base power has been the theme, with 10 of those hits going for doubles or homers. Defensively, the bullpen has been airtight, stringing together 7 1/3 scoreless frames across the two wins while allowing just five combined hits.
Nick Pivetta (11-4, 2.94 ERA) gets the start for San Diego, looking to rebound from a rough outing against Boston where he surrendered five runs in six innings. While he’s had mixed results against the Giants this year, eight runs allowed in 11 1/3 innings, the current Padres form gives them a strong edge in this spot. A win would further bury San Francisco in the division race and strengthen San Diego’s division title push.
San Francisco Giants Betting Preview
The Giants limp into the finale having lost 12 of their last 13 at home, scoring just 24 runs in that stretch and leaving an eye-popping 97 runners stranded. Their inability to cash in on scoring chances was on full display Tuesday when they loaded the bases with one out in the sixth inning, only to come up empty.
San Francisco will turn to Kai-Wei Teng (1-1, 5.40 ERA), who is coming off his first MLB win with five shutout innings against Washington. However, he was tagged for three runs in three innings in his debut against San Diego earlier this year, and the matchup again looks unfavorable given the Padres’ offensive surge.
The Giants’ postseason path is now more realistically tied to the Wild Card race, but to get back in the hunt, they need to break this home losing skid, something that’s easier said than done against a team playing at San Diego’s current level.
Betting Outlook & Prediction
San Diego’s combination of momentum, offensive depth, and bullpen dominance makes them the clear betting favorite here. Even with Pivetta’s uneven history against the Giants, the Padres’ bats and relief corps give them a significant edge.
Score Prediction: Padres 5, Giants 3
Pick: San Diego -1.5 (+107)
Total: Over 7.5 Atl Lines (-125)
- MLB Odds source: MyBookie Sportsbook
- Get real-time live scores & latest betting odds here!
