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Dodgers vs Giants Odds, Picks & Prediction Sunday

Expert betting preview for Dodgers vs Giants with odds, picks and score prediction for Sunday’s matchup.

(Photo by Getty Images) Emmet Sheehan
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San Francisco (76-79) at LA Dodgers (88-67)

  • When: Sep 21 2025, 4:10 PM
  • Where: Dodger Stadium, Los Angeles
  • Where to watch: NBCS-BA

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Moneyline: LA Dodgers -225 
Spread: LA Dodgers -1.5 (-110)
Total: 9.0

San Francisco Giants Betting Outlook

The Giants’ playoff hopes are dangling by a thread, and Sunday’s finale at Dodger Stadium could be their last gasp. After dropping seven of their last eight and staring at a 0.1% postseason probability, San Francisco desperately needs a spark. Bryce Eldridge, their 20-year-old top prospect, gave fans a glimpse of the future with a bases-clearing double Saturday, his first career hit and a moment of history.

Now rookie Trevor McDonald (0-0, 9.00 ERA) gets thrown into the fire for his first MLB start. He looked shaky in relief earlier this week, and facing a red-hot Dodgers lineup isn’t the friendliest assignment. Expect nerves, inconsistency, and some hard contact.

Player Prop to Watch – Bryce Eldridge (SF): To record 2+ Total Bases. The rookie has shown early confidence in RBI spots and could keep riding that momentum.

Los Angeles Dodgers Betting Outlook

The Dodgers are cruising, winners of four straight, and closing in on yet another NL West crown. With Will Smith sidelined by a fractured hand, LA still looks loaded, thanks to Shohei Ohtani and Freddie Freeman anchoring the offense.

Emmet Sheehan (6-3, 3.17 ERA) takes the ball, and he’s been dominant lately, just four earned runs allowed across his last 24.1 innings. Against the Giants, he’s been even sharper, sporting a 1.20 ERA in three career outings. If he stays in rhythm, the Dodgers should be in full control.

Player Prop to Watch – Freddie Freeman (LAD): To record 2+ Hits. Freeman has punished San Francisco pitching all year and thrives against young, inexperienced arms.

MLB Prediction & Betting Angle

The Giants are limping toward the finish line, while the Dodgers are sharpening up for October. San Francisco’s rookie-heavy roster feels overmatched, especially against a pitcher in Sheehan who knows how to handle them.

Score Prediction: Dodgers 6, Giants 3
Pick: LA Dodgers -1.5 (-110)
Total: Under 9.5 Alt Lines (-135) 

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