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Mariners vs Tigers MLB Baseball Odds & Parlay Picks

Seattle and Detroit will both be trying to pick up a win when they battle at Comerica Park.

(Photo by Getty Images) Tarik Skubal
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Seattle (48-45) at Detroit (59-35)

  • When: Jul 11 2025, 7:10 PM
  • Where: Comerica Park, Detroit
  • Where to watch: Apple TV+

Mariners vs. Tigers – Game Betting Preview & Prediction

Moneyline: Detroit -217 
Spread: Detroit -1.5 (+105)
Total: 7.0

Detroit Tigers Preview

The Tigers are rolling into this matchup behind their ace Tarik Skubal, whose All-Star form has been almost untouchable. Detroit shifted its rotation to keep Skubal on standard rest before he heads to Atlanta, and it’s clear why. The lefty is 10-2 with a nasty 2.02 ERA and has been lights out at home (8-0, 2.06 ERA).

Skubal hasn’t allowed a run in his last 18 innings, with 23 strikeouts and just one walk over that span. When he’s locked in, he’s nearly impossible to square up. Detroit’s recent five-game win streak was halted by Tampa Bay, but the Tigers are rested and hunting for their 60th win.

With their ace on the mound and a solid 27-18 home record, Detroit looks like a confident pick to handle business at Comerica.

Seattle Mariners Preview

Seattle comes in with momentum issues after blowing a 5-0 lead and losing in extras to the Yankees on Thursday, which capped off a brutal sweep. Luis Castillo (5-5, 3.31 ERA) will try to stop the bleeding. The righty has looked sharp recently, tossing 13 scoreless innings over his last two starts.

However, his track record against Detroit isn’t promising (1-4, 3.75 ERA), and the Mariners’ inconsistency at the plate has made winning on the road a challenge.

Prediction & Betting Picks

The Tigers are heavy favorites, and deservedly so. Skubal is pitching like a Cy Young contender, and Detroit’s offense has been hot at home. Meanwhile, Seattle is coming off an emotional letdown and will be tasked with facing one of the league’s best arms. Expect a low-scoring game, with Detroit pulling off a clean win.

Score Prediction: Tigers 4, Mariners 2
Pick: Detroit -1.5 (+105)
Total: Under 7.0 (-120)  

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