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Mariners vs Angels MLB Baseball Odds & Expert Picks

The division rival Seattle and LA Angels are set to renew hostilities when they meet at Angel Stadium.

(Photo by Getty Images) Julio Rodriguez
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Seattle (55-49) at LA Angels (50-54)

  • When: Jul 26 2025, 9:38 PM
  • Where: Angel Stadium, Anaheim
  • Where to watch: ROOT Sports NW

Mariners vs Angels – Game Preview, Prediction and Player Props

Moneyline: Seattle -135
Total: 8.5
RunLine: Seattle -1.5 (+125)

Seattle Mariners Betting Outlook

Seattle turns to George Kirby, their strike-throwing right-hander, who will face the Angels for the second time this season. Kirby (4-5, 4.65 ERA) dominated Los Angeles in their June 8 meeting, setting a career high with 14 strikeouts in seven innings, allowing just a two-run homer to Taylor Ward.

The Mariners are clinging to the second AL wild-card spot and need a strong outing from Kirby to bounce back from Friday’s 3-2 loss in 10 innings. Kirby has historically performed well against Los Angeles, going 5-4 with a 3.52 ERA in nine career starts, including 4-2 with a 3.38 ERA in Anaheim.

Julio Rodriguez remains Seattle’s offensive catalyst. His two solo homers on Friday marked the fifth multi-homer game of his young career, joining Ken Griffey Jr. and Alex Rodriguez as the only Mariners to accomplish that feat by age 24. Seattle’s recent acquisition, Josh Naylor, also made his debut, going 1-for-4.

Seattle Player Prop Pick:
Julio Rodriguez Over 1.5 Total Bases – Rodriguez is seeing the ball well and thrives against Los Angeles pitching.

Los Angeles Angels Betting Outlook

The Angels snapped a four-game losing streak on Friday with a dramatic walk-off by Zach Neto, who capped his bobblehead night with his first career walk-off hit. Los Angeles sits 4.5 games back of the final AL wild-card spot and is fighting to stay relevant ahead of the trade deadline.

Tyler Anderson (2-6, 4.43 ERA) takes the mound and will look to reverse his luck against Seattle. Anderson has struggled historically versus the Mariners, holding a 1-3 record with a 5.01 ERA across 10 starts. He also lost the June 8 matchup, surrendering three runs on eight hits in just 4 2/3 innings.

Trade rumors are swirling around the Angels, with multiple veterans potentially on the move. However, performances like Friday’s victory are the kind of spark the team needs to hold onto hope.

Los Angeles Player Prop Pick:
Taylor Ward to Record an RBI – Ward has hit Kirby well and remains one of the Angels’ most consistent bats.

Game Prediction & Betting Lean

Kirby’s dominance against Los Angeles and Seattle’s push for a postseason berth give them the edge in this matchup. Expect Rodriguez to stay hot and Seattle to lean on its pitching advantage.

Final Score Prediction: Mariners 5, Angels 3
Lean: Seattle (-135)
Total: 
Under 8.5 (-110) 

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