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Seahawks vs Bucs Week 5 Odds, Preview & Prediction

Betting odds, prediction & matchup preview for Seahawks vs Buccaneers in Week 5.

(Photo by Getty Images) Sam Darnold
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Tampa Bay (3-1-0) at Seattle (3-1-0)

  • When: Oct 5 2025, 4:05 PM
  • Where: Lumen Field, Seattle, WA
  • Where to watch: CBS
  • Last Meeting: TB 21-16, November 13th, 2022

Tampa Bay vs Seattle Preview & Prediction

Spread: Seattle -3.5
Moneyline: Seattle (-195)
Total: 44.5

Seattle Seahawks Betting Breakdown

The Seahawks are riding a 3-1 start with Sam Darnold proving he’s not just a reclamation project but a legitimate franchise QB. Seattle’s investment in Darnold has started to pay off, especially with the help of a stingy secondary that’s already racked up 7 interceptions in just four games, more than half their total from all of last year.

Seattle’s defensive unit has found cohesion, with head coach Mike Macdonald crediting speed, physicality, and aggression as the foundation of their success. That makes them dangerous against a Buccaneers team dealing with injuries and protection issues.

Offensively, the Seahawks remain balanced, even if their run game has been inconsistent. Macdonald remains committed to pounding the rock regardless of opponent trends, which could test Tampa Bay’s top-10 run defense. Still, the bigger edge might come from Darnold picking apart a depleted Tampa secondary with quick reads and clean pocket presence.

Tampa Bay Buccaneers Betting Breakdown

The Buccaneers are also 3-1, but it hasn’t been a smooth ride. Baker Mayfield continues his redemption arc and leads the league in touchdown passes since joining Tampa. That said, he’s now operating behind a banged-up offensive line and without his top weapon, Mike Evans, who is sidelined with a hamstring injury.

Defensively, Tampa Bay remains one of the best units against the run, allowing the fifth-fewest rushing yards per game. But the loss of key depth pieces and special teams miscues, including blocked punts and missed protections, have put them in compromising field positions far too often.

The Bucs will likely lean on their short passing game and ball control to stay close, but unless the defense creates turnovers, it’s tough to see them outlasting Seattle for four quarters.

NFL Final Score Prediction

Seattle’s defensive playmaking is the difference-maker here. The Seahawks are generating takeaways at an elite clip and facing a Tampa offense that’s down key starters and struggling on special teams. Combine that with Sam Darnold’s efficient, mistake-free football and a balanced offensive scheme, and Seattle is well-positioned to control the tempo and cover the number at home. The Bucs keep it close early, but the Seahawks pull away late.

Final Score: Seahawks 23, Buccaneers 17
Lean: Seattle -3.5
Total: 
Under 44.5 

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