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San Francisco (60-64) at San Diego (69-55)
- When: Aug 18 2025, 9:40 PM
- Where: PETCO Park, San Diego
- Where to watch: SDPA
Giants vs Padres – Game Preview, Prediction and Player Props
Moneyline: San Diego -147
Total: 7.5
RunLine: San Diego -1.5 (+152)
The Padres return home looking for redemption after being swept in Los Angeles, while the Giants try to shake off their Oracle Park blues. Both teams send lefties to the mound Monday night in what should be a tight divisional matchup.
San Diego Padres Betting Outlook
San Diego limps into this series after a frustrating sweep by the Dodgers that knocked them two games out of first in the NL West. They’ll turn to newly-acquired southpaw Nestor Cortes (1-1, 5.71 ERA), who impressed against the Giants last week with six strikeouts over 4 2/3 innings.
The concern is their banged-up lineup, especially with Jackson Merrill dealing with yet another injury, this time an ankle tweak. Still, the Padres have dominated the Giants this season (7-2 head-to-head), outscoring them 20-3 in last week’s sweep.
Player Prop to Watch (Padres): Manny Machado Over 1.5 Total Bases – he’s historically hit Robbie Ray well and could deliver at least one big extra-base hit.
San Francisco Giants Betting Outlook
San Francisco finally snapped its seven-game skid with a 7-1 win over Tampa Bay, but the bigger story is how bad they’ve been at home. Luckily for them, this series is on the road, where they’ve at least been somewhat competitive.
Robbie Ray (9-6, 2.98 ERA) gets the start after losing to San Diego last week. He’s 1-1 vs. the Padres this year but owns a shaky 4.25 ERA lifetime against them. The Giants will need his best stuff, especially with their lineup struggling for consistency.
Player Prop to Watch (Giants): Willy Adames to Record a Run – he’s been aggressive on the bases and brings an extra spark when San Francisco’s bats are sluggish.
MLB Prediction & Betting Angle
San Diego owns the matchup edge, the home crowd, and a deeper bullpen. The Giants are just too inconsistent and Cortes has shown enough to keep them in check. Expect San Diego’s bats to break through against Ray late.
Final Score Prediction: Padres 5, Giants 3
Lean: San Diego -1.5 (+152)
Total: Over 7.5 (-108)
- MLB Odds source: MyBookie Sportsbook
- Get real-time live scores & latest betting odds here!
